INT160971

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Context Info
Confidence 0.01
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.16
Pain Relevance 0.41

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Grm7) Golgi apparatus (Grm7) plasma membrane (Grm7)
neurological system process (Grm7) protein complex (Grm7) signal transducer activity (Grm7)
Anatomy Link Frequency
synapse 1
Gm2111 (Mus musculus)
Grm7 (Mus musculus)
Pain Link Frequency Relevance Heat
GABAergic 1 100.00 Very High Very High Very High
agonist 4 96.60 Very High Very High Very High
Glutamate 1 88.88 High High
Dopamine 1 86.88 High High
palliative 1 79.80 Quite High
Glutamate receptor 1 75.00 Quite High
Disease Link Frequency Relevance Heat
Disease 1 81.20 Quite High
Parkinsonian Disorders 1 75.00 Quite High
Catalepsy 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In mouse brain slices, LSP1-2111 inhibits striatopallidal GABAergic transmission by selectively activating the mGlu4 receptor but has no effect at a synapse modulated solely by the mGlu7 and mGlu8 receptors.
LSP1-2111 Positive_regulation (activating) of mGlu4 receptor in synapse associated with gabaergic
1) Confidence 0.01 Published 2009 Journal FASEB J. Section Abstract Doc Link 19525404 Disease Relevance 0.16 Pain Relevance 0.41

General Comments

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