INT16104

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Context Info
Confidence 0.03
First Reported 1991
Last Reported 2000
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 0.53
Pain Relevance 0.14

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (GNRH1) extracellular space (GNRH1) extracellular region (GNRH1)
cell-cell signaling (GNRH1)
GNRH1 (Homo sapiens)
Lhb (Mus musculus)
Pain Link Frequency Relevance Heat
agonist 3 91.16 High High
Pain 2 62.32 Quite High
palliative 1 25.00 Low Low
Disease Link Frequency Relevance Heat
Obesity 2 95.44 Very High Very High Very High
Precocious Puberty 2 79.92 Quite High
Hamartoma 3 78.16 Quite High
Pain 2 62.32 Quite High
Prostate Cancer 3 62.00 Quite High
Reprotox - General 1 1 25.00 Low Low
Hyperplasia 1 25.00 Low Low
Toxicity 1 25.00 Low Low
Increased Venous Pressure Under Development 1 25.00 Low Low
Benign Prostatic Hypertrophy 1 25.00 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We found that the patients' mean +/- SD peak GnRH-stimulated LH and FSH had returned to the normal range by 1 yr after stopping therapy.
GnRH Positive_regulation (stimulated) of LH
1) Confidence 0.03 Published 2000 Journal J. Clin. Endocrinol. Metab. Section Abstract Doc Link 11095429 Disease Relevance 0.47 Pain Relevance 0.14
Leuprorelin (leuprolide acetate) is a synthetic analogue of gonadotrophin-releasing hormone (GnRH) [luteinising hormone-releasing hormone (LHRH)] which initially stimulates luteinising hormone (LH) and hence testicular androgen release; continuous administration then results in profound suppression of these hormones.
gonadotrophin-releasing hormone Positive_regulation (stimulates) of LH
2) Confidence 0.00 Published 1991 Journal Drugs Aging Section Abstract Doc Link 1794035 Disease Relevance 0.06 Pain Relevance 0

General Comments

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