INT161175

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.32
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 2
Disease Relevance 1.49
Pain Relevance 0.23

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (Mapk1) mitochondrion (Mapk1) transport (Trpc6)
protein complex (Mapk1) cytoplasm (Mapk1) transmembrane transport (Trpc6)
Anatomy Link Frequency
podocytes 2
Trpc6 (Mus musculus)
Mapk1 (Mus musculus)
Pain Link Frequency Relevance Heat
Calcium channel 2 76.64 Quite High
member 8 2 75.40 Quite High
Disease Link Frequency Relevance Heat
Apoptosis 18 98.36 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Treated with extracellular signal-regulated kinase (ERK) pathway specific inhibitor U0126 or nuclear factor-kappaB (NF-kappaB) pathway specific inhibitor ammonium pyrrolidinedithiocarbamate (PDTC) and Ang II, respectively in podocytes, not only was the TRPC6 up-regulation reduced, but the podocyte apoptosis was also decreased.
TRPC6 Binding (Treated) of ERK in podocytes associated with apoptosis
1) Confidence 0.32 Published 2009 Journal Exp. Biol. Med. (Maywood) Section Abstract Doc Link 19546355 Disease Relevance 0.74 Pain Relevance 0.11
Treated with extracellular signal-regulated kinase (ERK) pathway specific inhibitor U0126 or nuclear factor-kappaB (NF-kappaB) pathway specific inhibitor ammonium pyrrolidinedithiocarbamate (PDTC) and Ang II, respectively in podocytes, not only was the TRPC6 up-regulation reduced, but the podocyte apoptosis was also decreased.
TRPC6 Binding (Treated) of extracellular signal-regulated kinase in podocytes associated with apoptosis
2) Confidence 0.32 Published 2009 Journal Exp. Biol. Med. (Maywood) Section Abstract Doc Link 19546355 Disease Relevance 0.74 Pain Relevance 0.11

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox