INT161182

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Context Info
Confidence 0.41
First Reported 2006
Last Reported 2009
Negated 0
Speculated 1
Reported most in Body
Documents 1
Total Number 3
Disease Relevance 1.83
Pain Relevance 1.35

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (NMS)
Anatomy Link Frequency
RVM 1
NMS (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Rostral ventromedial medulla 4 100.00 Very High Very High Very High
amygdala 3 100.00 Very High Very High Very High
Neurotransmitter 190 99.76 Very High Very High Very High
Neuropeptide 24 99.24 Very High Very High Very High
Pain 6 97.76 Very High Very High Very High
Intracerebroventricular 6 91.44 High High
nud 2 88.64 High High
Eae 12 77.28 Quite High
gABA 60 62.56 Quite High
Glutamate 44 62.24 Quite High
Disease Link Frequency Relevance Heat
Neuroleptic Malignant Syndrome 19 100.00 Very High Very High Very High
Pain 4 97.76 Very High Very High Very High
Dyspepsia 2 88.64 High High
Stress 1 87.44 High High
Nociception 1 86.48 High High
Hypertension 18 5.00 Very Low Very Low Very Low
Sleep Disorders 16 5.00 Very Low Very Low Very Low
Affective Disorder 16 5.00 Very Low Very Low Very Low
Disease 14 5.00 Very Low Very Low Very Low
Cancer 10 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The present study aimed to investigate changes in the expression of BDNF and its receptor tyrosine kinase receptor B (TrkB) in the amygdala and the rostral ventromedial medulla (RVM) after NMS and colorectal distention (CRD) stimulation in rats.
Spec (investigate) Gene_expression (expression) of NMS in RVM associated with neuroleptic malignant syndrome, amygdala and rostral ventromedial medulla
1) Confidence 0.41 Published 2009 Journal Neurosignals Section Abstract Doc Link 19546592 Disease Relevance 1.09 Pain Relevance 0.53
NMS expression is found to be restricted to the core part of the SCN and has a diurnal peak under light-dark cycle [96].
Gene_expression (expression) of NMS associated with neuroleptic malignant syndrome
2) Confidence 0.14 Published 2006 Journal J Circadian Rhythms Section Body Doc Link PMC1402333 Disease Relevance 0.40 Pain Relevance 0.41
A recent addition to the ever increasing list of neurotransmitters of the SCN is neuromedin S (NMS), a 36 amino acid neuropeptide.
Gene_expression (is) of NMS associated with neurotransmitter, neuroleptic malignant syndrome and neuropeptide
3) Confidence 0.12 Published 2006 Journal J Circadian Rhythms Section Body Doc Link PMC1402333 Disease Relevance 0.34 Pain Relevance 0.41

General Comments

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