INT161187

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Context Info
Confidence 0.43
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 3
Disease Relevance 3.05
Pain Relevance 2.06

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Ntrk2) endosome (Ntrk2) aging (Ntrk2)
extracellular region (NMS) plasma membrane (Ntrk2)
Anatomy Link Frequency
RVM 5
amygdala 1
NMS (Rattus norvegicus)
Ntrk2 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
amygdala 9 99.48 Very High Very High Very High
Rostral ventromedial medulla 12 98.96 Very High Very High Very High
Pain 18 89.84 High High
nud 6 84.32 Quite High
nociceptor 3 25.00 Low Low
Disease Link Frequency Relevance Heat
Neuroleptic Malignant Syndrome 27 100.00 Very High Very High Very High
Pain 12 77.48 Quite High
Dyspepsia 6 68.36 Quite High
Stress 3 67.16 Quite High
Nociception 3 66.20 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
An interactive effect of NMS and CRD on the expression of TrkB, but not BDNF, was found in the RVM.
NMS Regulation (effect) of Gene_expression (expression) of TrkB in RVM associated with neuroleptic malignant syndrome and rostral ventromedial medulla
1) Confidence 0.43 Published 2009 Journal Neurosignals Section Abstract Doc Link 19546592 Disease Relevance 1.05 Pain Relevance 0.67
Furthermore, a significant interactive effect of NMS and CRD on the colocalization coefficient of TrkB and phospho-extracellular signal-regulated kinase expression in both the amygdala and RVM were found.
NMS Regulation (effect) of Gene_expression (expression) of TrkB in RVM associated with neuroleptic malignant syndrome, amygdala and rostral ventromedial medulla
2) Confidence 0.31 Published 2009 Journal Neurosignals Section Abstract Doc Link 19546592 Disease Relevance 1.00 Pain Relevance 0.69
Furthermore, a significant interactive effect of NMS and CRD on the colocalization coefficient of TrkB and phospho-extracellular signal-regulated kinase expression in both the amygdala and RVM were found.
NMS Regulation (effect) of in amygdala Gene_expression (expression) of TrkB in RVM associated with neuroleptic malignant syndrome, amygdala and rostral ventromedial medulla
3) Confidence 0.11 Published 2009 Journal Neurosignals Section Abstract Doc Link 19546592 Disease Relevance 1.00 Pain Relevance 0.69

General Comments

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