INT161188

Context Info Confidence 0.03 First Reported 2009 Last Reported 2009 Negated 0 Speculated 0 Reported most in Abstract Documents 1 Total Number 2 Disease Relevance 2.00 Pain Relevance 1.39

extracellular region (NMS)

Anatomy Link Frequency RVM 3 amygdala 1 NMS (Rattus norvegicus) Rvm (Mus musculus)

Pain Link Frequency Relevance Heat Rostral ventromedial medulla 8 100.00 amygdala 6 100.00 Pain 12 92.16 nud 4 86.64 nociceptor 2 25.00

Disease Link Frequency Relevance Heat Neuroleptic Malignant Syndrome 18 100.00 Pain 8 75.00 Dyspepsia 4 63.40 Stress 2 62.20 Nociception 2 61.24

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Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Furthermore, a significant interactive effect of NMS and CRD on the colocalization coefficient of TrkB and phospho-extracellular signal-regulated kinase expression in both the amygdala and RVM were found.

NMS Regulation (effect) of Gene_expression (expression) of RVM in RVM associated with neuroleptic malignant syndrome, amygdala and rostral ventromedial medulla

1) Confidence 0.03 Published 2009 Journal Neurosignals Section Abstract Doc Link 19546592 Disease Relevance 1.00 Pain Relevance 0.70

Furthermore, a significant interactive effect of NMS and CRD on the colocalization coefficient of TrkB and phospho-extracellular signal-regulated kinase expression in both the amygdala and RVM were found.

NMS Regulation (effect) of in amygdala Gene_expression (expression) of RVM in RVM associated with neuroleptic malignant syndrome, amygdala and rostral ventromedial medulla

2) Confidence 0.01 Published 2009 Journal Neurosignals Section Abstract Doc Link 19546592 Disease Relevance 1.00 Pain Relevance 0.70

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