INT161264

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Context Info
Confidence 0.40
First Reported 2007
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.94
Pain Relevance 0.18

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

hydrolase activity, acting on glycosyl bonds (Hexb) carbohydrate metabolic process (Hexb) lysosome (Hexb)
Anatomy Link Frequency
mast cells 1
Hexb (Mus musculus)
Pain Link Frequency Relevance Heat
cytokine 5 96.04 Very High Very High Very High
Inflammation 35 72.80 Quite High
Pain 1 71.80 Quite High
Central nervous system 15 55.60 Quite High
chemokine 3 21.64 Low Low
dexamethasone 4 5.00 Very Low Very Low Very Low
Demyelination 4 5.00 Very Low Very Low Very Low
Inflammatory response 3 5.00 Very Low Very Low Very Low
ketamine 2 5.00 Very Low Very Low Very Low
cerebral cortex 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Hypersensitivity 4 97.32 Very High Very High Very High
Anaphylaxis 2 88.68 High High
Eczema 3 81.60 Quite High
Disease 7 73.12 Quite High
INFLAMMATION 38 72.80 Quite High
Pain 1 71.80 Quite High
Diabetes Mellitus 1 71.56 Quite High
Repression 4 64.92 Quite High
Death 7 50.00 Quite Low
Infection 11 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
At the cell level, the hexane fraction markedly inhibited beta-hexosaminidase release from RBL-2H3 mast cells and suppressed the expressions of mRNA interferon-gamma and interleukin-4 cytokines produced by T helper cells (type 1 and 2).
Localization (release) of beta-hexosaminidase in mast cells associated with cytokine
1) Confidence 0.40 Published 2009 Journal Arch. Pharm. Res. Section Abstract Doc Link 19557358 Disease Relevance 0.87 Pain Relevance 0.16
Figure 4 depicts results for the validation of Cd44, Stat1, Ch25h, Il1b, C1qa and Hexb.
Localization (validation) of Hexb
2) Confidence 0.32 Published 2007 Journal PLoS ONE Section Body Doc Link PMC1819560 Disease Relevance 0.06 Pain Relevance 0.03

General Comments

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