INT161276

Context Info Confidence 0.38 First Reported 2004 Last Reported 2010 Negated 1 Speculated 2 Reported most in Body Documents 7 Total Number 9 Disease Relevance 1.43 Pain Relevance 1.40

cell differentiation (NHS) nucleus (NHS)

NHS (Homo sapiens)

Pain Link Frequency Relevance Heat methadone 1 98.28 Buprenorphine 1 97.72 Acupuncture 54 94.80 opiate 1 93.68 backache 22 89.96 Pain 34 80.96 Morphine 1 36.56 cocaine 10 30.72 headache 8 5.00 drug abuse 7 5.00

Disease Link Frequency Relevance Heat Disease 88 99.04 Diabetes Mellitus 6 97.20 Respiratory Disease 1 91.92 Low Back Pain 29 89.96 Pain 23 80.96 Nose Bleeds 6 73.48 Overdose 7 64.80 Cardiovascular Disease 1 63.28 Hepatitis C Virus Infection 3 51.40 Hepatitis B Virus Infection 3 51.08

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

The informants in this study included older people who paid NHS charges for dental treatment, those who were partially or fully exempt from NHS charges and people who paid for private treatment.

Regulation (paid) of NHS

1) Confidence 0.38 Published 2008 Journal BMC Oral Health Section Body Doc Link PMC2335092 Disease Relevance 0 Pain Relevance 0

Cost-effectiveness was calculated from both NHS and societal perspectives including NHS costs, private treatment costs and the cost of lost productivity.

Regulation (calculated) of NHS

2) Confidence 0.27 Published 2006 Journal Evidence-based Complementary and Alternative Medicine Section Body Doc Link PMC1697737 Disease Relevance 0.65 Pain Relevance 0.98

Research undertaken in academia has certainly highlighted the benefits of spatial statistics and GIS approaches in mapping disease and in healthcare planning, but still needs to respond to NHS needs on the ground.

Regulation (respond) of NHS associated with disease

3) Confidence 0.25 Published 2004 Journal Int J Health Geogr Section Body Doc Link PMC343292 Disease Relevance 0.10 Pain Relevance 0

CONCLUSIONS: An inappropriate referral rate of approximately 52% was encountered that had a significant impact on the waiting time for the proposed test (5.7 months), which is far longer than the 18-week target for treatment in the NHS.

Regulation (target) of NHS

4) Confidence 0.23 Published 2009 Journal Ann R Coll Surg Engl Section Body Doc Link 19558765 Disease Relevance 0 Pain Relevance 0

In the UK, the National Institute for Health and Clinical Excellence (NICE) considers evidence of both clinical and cost effectiveness when deciding on whether or not to sanction the introduction of new NHS treatments or services.

Spec (whether) Regulation (introduction) of NHS

5) Confidence 0.17 Published 2008 Journal Cost Eff Resour Alloc Section Body Doc Link PMC2292150 Disease Relevance 0 Pain Relevance 0

NHS Direct decided to extend its services to the Internet, introducing NHS Direct Online in 1999 [5].

Regulation (introducing) of NHS

6) Confidence 0.03 Published 2004 Journal Journal of Medical Internet Research Section Body Doc Link PMC1550598 Disease Relevance 0 Pain Relevance 0

Recent empirical work on the efficiency of different clinical specialties in the NHS suggests that £245?

Regulation (specialties) of NHS

7) Confidence 0.03 Published 2010 Journal BMJ : British Medical Journal Section Body Doc Link PMC2808469 Disease Relevance 0.25 Pain Relevance 0

A King's College Hospital Study commissioned by the Department of Health has suggested that day-case surgery may not be saving the NHS money [3].

Neg (not) Spec (may) Regulation (saving) of NHS

8) Confidence 0.02 Published 2004 Journal BMC Ear Nose Throat Disord Section Body Doc Link PMC526258 Disease Relevance 0.21 Pain Relevance 0.14

All types of treatment used in the NHS treatment centres are recorded: pharmacological treatments (methadone and buprenorphine maintenance or detoxification, psychotropic drugs, naltrexone, detoxification with non-opiate drugs), psychosocial treatments (counselling, social advice, psychotherapy, job guidance), in-patient detoxification, semi-residential treatment and residential therapeutic community. 2.5 Biological sample

Regulation (centres) of NHS associated with opiate, methadone and buprenorphine

9) Confidence 0.02 Published 2007 Journal Subst Abuse Treat Prev Policy Section Body Doc Link PMC1838901 Disease Relevance 0.22 Pain Relevance 0.29

General Comments

This test has worked.