INT161298

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.05
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.16
Pain Relevance 0.70

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (Ppp1r1b, Trib3) cytosol (Ppp1r1b) nucleolus (Trib3)
intracellular (Ppp1r1b) enzyme binding (Trib3) kinase activity (Trib3)
Ppp1r1b (Rattus norvegicus)
Trib3 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Dopamine 10 97.80 Very High Very High Very High
Morphine 8 85.00 Quite High
antagonist 3 82.92 Quite High
Glutamate receptor 1 66.88 Quite High
Nucleus accumbens 1 52.96 Quite High
opioid receptor 1 36.64 Quite Low
Disease Link Frequency Relevance Heat
Stress 3 79.64 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Since DARPP-32 phosphorylated in Thr75 inhibits cAMP-dependent protein kinase (PKA) activity, the final result is a decrease in the dopamine D(1) receptor-dependent phosphorylation events.
DARPP-32 Negative_regulation (inhibits) of kinase associated with dopamine
1) Confidence 0.05 Published 2009 Journal Neuroscience Section Abstract Doc Link 19559764 Disease Relevance 0.16 Pain Relevance 0.70

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox