INT161321

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Context Info
Confidence 0.68
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 2.05
Pain Relevance 0.89

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (Smarcb1) nuclear chromosome (Smarcb1) nucleolus (Smarcb1)
nucleus (Smarcb1) cell cycle (Smarcb1)
Anatomy Link Frequency
Nociceptors 1
Smarcb1 (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammatory mediators 2 99.98 Very High Very High Very High
nociceptor 2 98.68 Very High Very High Very High
Lasting pain 4 96.44 Very High Very High Very High
Neurotransmitter 1 91.96 High High
dorsal root ganglion 103 90.08 High High
Pain 7 87.84 High High
Spinal cord 9 86.08 High High
Inflammation 55 84.12 Quite High
Peripheral nerve injury 17 81.60 Quite High
headache 1 66.84 Quite High
Disease Link Frequency Relevance Heat
INFLAMMATION 66 99.78 Very High Very High Very High
Cancer 12 99.16 Very High Very High Very High
Necrosis 2 98.88 Very High Very High Very High
Pain 11 96.44 Very High Very High Very High
Ganglion Cysts 103 89.12 High High
Primitive Neuroectodermal Tumors 2 83.72 Quite High
Nervous System Injury 31 80.72 Quite High
Vomiting 1 67.36 Quite High
Headache 1 66.84 Quite High
Pancreatitis 7 58.08 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Nociceptors are known to be sensitized by a number of inflammatory mediators released from damaged tissues, such as ATP, nitric oxide, interleukin 1, interleukin 6, and tumour necrosis factor alpha (TNF-?)
Localization (released) of in 1 in Nociceptors associated with necrosis, inflammatory mediators, cancer and nociceptor
1) Confidence 0.68 Published 2010 Journal Mol Pain Section Body Doc Link PMC2873504 Disease Relevance 1.24 Pain Relevance 0.82
Mutation analysis did not show any variation in INI-1 and PTEN sequence while P53 analysis showed the presence of homozygote P72R variation.
Localization (sequence) of INI-1
2) Confidence 0.06 Published 2010 Journal Neuropathology Section Abstract Doc Link 19563506 Disease Relevance 0.81 Pain Relevance 0.07

General Comments

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