INT161389

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Context Info
Confidence 0.21
First Reported 2009
Last Reported 2009
Negated 1
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 1.06
Pain Relevance 0.59

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (PNOC) extracellular region (PNOC)
Anatomy Link Frequency
temporal lobe 2
PNOC (Homo sapiens)
Pain Link Frequency Relevance Heat
orphanin 9 100.00 Very High Very High Very High
Opioid 3 76.84 Quite High
Disease Link Frequency Relevance Heat
Sclerosis 3 98.88 Very High Very High Very High
Cancer 1 97.24 Very High Very High Very High
Convulsion 1 96.72 Very High Very High Very High
Epilepsy 7 96.00 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Patients with temporal lobe epilepsy associated with mesial sclerosis (MTLE) or secondary to tumor or vascular lesion showed enhanced [3H]DAMGO and [3H]forskolin binding, lower DAMGO-stimulated [35S]GTPgammaS binding and no significant changes in nociceptin-stimulated G-protein. [3H]Nociceptin binding was lower in patients with MTLE.
Neg (no) Regulation (changes) of Nociceptin Binding (binding) of in temporal lobe associated with epilepsy, cancer, orphanin and sclerosis
1) Confidence 0.21 Published 2009 Journal Neurobiol. Dis. Section Abstract Doc Link 19573600 Disease Relevance 1.06 Pain Relevance 0.59

General Comments

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