INT161411

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Context Info
Confidence 0.44
First Reported 2009
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 1.43
Pain Relevance 1.12

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transport (Slc17a5) cytoplasmic membrane-bounded vesicle (Slc17a5) plasma membrane (Slc17a5)
transmembrane transport (Slc17a5) lysosome (Slc17a5)
Anatomy Link Frequency
liver 2
Slc17a5 (Mus musculus)
Pain Link Frequency Relevance Heat
ischemia 66 99.92 Very High Very High Very High
Paracetamol 8 99.68 Very High Very High Very High
Inflammation 8 79.16 Quite High
cytokine 4 5.00 Very Low Very Low Very Low
isoflurane 2 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
Inflammatory response 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cv Unclassified Under Development 66 99.92 Very High Very High Very High
Hepatitis 2 88.84 High High
Stress 16 86.40 High High
Injury 33 82.92 Quite High
INFLAMMATION 8 79.16 Quite High
Sprains And Strains 4 78.48 Quite High
Pressure And Volume Under Development 2 37.44 Quite Low
Necrosis 3 5.00 Very Low Very Low Very Low
Reperfusion Injury 3 5.00 Very Low Very Low Very Low
Sepsis 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Elevation of serum ALT and AST activities, decrease of reduced glutathione levels and histopathological liver changes were observed to the same extents in both APAP-treated groups.
Positive_regulation (Elevation) of Localization (decrease) of AST in liver associated with paracetamol
1) Confidence 0.44 Published 2009 Journal Toxicology Section Abstract Doc Link 19576946 Disease Relevance 0.22 Pain Relevance 0.72
AST release occurred earlier (0.5–1.5?
Positive_regulation (occurred) of Localization (release) of AST
2) Confidence 0.04 Published 2010 Journal Mediators of Inflammation Section Body Doc Link PMC3010695 Disease Relevance 1.21 Pain Relevance 0.40

General Comments

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