INT161455

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Context Info
Confidence 0.03
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 2
Disease Relevance 0.19
Pain Relevance 0.92

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endosome (Egfr) cell morphogenesis (Egfr) intracellular (Egfr)
enzyme binding (Egfr) cytoplasm (Egfr) signal transducer activity (Egfr)
Mmp7 (Rattus norvegicus)
Egfr (Rattus norvegicus)
Pain Link Frequency Relevance Heat
metalloproteinase 8 100.00 Very High Very High Very High
bradykinin 8 98.48 Very High Very High Very High
Opioid 2 97.92 Very High Very High Very High
Disease Link Frequency Relevance Heat
Myocardial Infarction 2 93.20 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Muscarinic and opioid G-protein-coupled receptors are equally protective and have been shown to couple through a matrix metalloproteinase (MMP)-dependent transactivation of the epidermal growth factor receptor (EGFR).
metalloproteinase Positive_regulation (transactivation) of EGFR associated with metalloproteinase and opioid
1) Confidence 0.03 Published 2009 Journal Acta Physiol (Oxf) Section Abstract Doc Link 19583703 Disease Relevance 0.09 Pain Relevance 0.46
Muscarinic and opioid G-protein-coupled receptors are equally protective and have been shown to couple through a matrix metalloproteinase (MMP)-dependent transactivation of the epidermal growth factor receptor (EGFR).
metalloproteinase Positive_regulation (transactivation) of epidermal growth factor receptor associated with metalloproteinase and opioid
2) Confidence 0.03 Published 2009 Journal Acta Physiol (Oxf) Section Abstract Doc Link 19583703 Disease Relevance 0.09 Pain Relevance 0.46

General Comments

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