INT161507

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Context Info
Confidence 0.24
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.19
Pain Relevance 1.25

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Il1b) signal transduction (Tlr4) aging (Il1b)
extracellular region (Il1b) plasma membrane (Tlr4) intracellular (Tlr4)
Tlr4 (Mus musculus)
Il1b (Mus musculus)
Pain Link Frequency Relevance Heat
Paracetamol 12 100.00 Very High Very High Very High
cytokine 7 94.88 High High
Inflammation 4 90.72 High High
Disease Link Frequency Relevance Heat
INFLAMMATION 4 75.00 Quite High
Toxicity 1 51.04 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Furafylline, a CYP1A inhibitor, and indomethacin, a PGHS inhibitor, exhibited a significant inhibitory effect on TNFalpha and IL-1beta production induced by the APAP and LPS combination.
LPS Positive_regulation (induced) of Gene_expression (production) of IL-1beta associated with paracetamol
1) Confidence 0.24 Published 2009 Journal J Immunotoxicol Section Abstract Doc Link 19589095 Disease Relevance 0.19 Pain Relevance 1.25

General Comments

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