INT161520

Context Info Confidence 0.09 First Reported 2009 Last Reported 2009 Negated 1 Speculated 0 Reported most in Abstract Documents 1 Total Number 1 Disease Relevance 0.47 Pain Relevance 0.79

nucleoplasm (Mapk1) mitochondrion (Mapk1) protein complex (Mapk1) cytoplasm (Mapk1) cytosol (Mapk1) signal transduction (Mapk1)

H2-M3 (Mus musculus) Mapk1 (Mus musculus)

Pain Link Frequency Relevance Heat Pain 3 98.44 Spinal cord 2 91.04 nMDA receptor 1 88.28 antagonist 2 86.24 nMDA receptor antagonist 1 82.92 substance P 2 81.20 Morphine 3 75.00 Analgesic 3 67.08 intrathecal 1 63.12 nociceptor 1 25.00

Disease Link Frequency Relevance Heat Pain 2 98.44 Nociception 5 92.32

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Here, we investigated whether M3G could influence the ERK activation in the NO-cGMP-PKG pathway.

M3G Neg (NO) Regulation (influence) of Positive_regulation (activation) of ERK

1) Confidence 0.09 Published 2009 Journal Biochem. Pharmacol. Section Abstract Doc Link 19589334 Disease Relevance 0.47 Pain Relevance 0.79

General Comments

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