INT161522

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Context Info
Confidence 0.15
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.41
Pain Relevance 0.41

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (Mapk1) mitochondrion (Mapk1) protein complex (Mapk1)
cytoplasm (Mapk1) cytosol (Mapk1) signal transduction (Mapk1)
Anatomy Link Frequency
spinal cord 1
H2-M3 (Mus musculus)
Mapk1 (Mus musculus)
Pain Link Frequency Relevance Heat
Spinal cord 2 99.68 Very High Very High Very High
Morphine 3 75.00 Quite High
Pain 3 74.24 Quite High
nMDA receptor 1 64.08 Quite High
antagonist 2 62.04 Quite High
nMDA receptor antagonist 1 58.72 Quite High
substance P 2 57.00 Quite High
Analgesic 3 42.88 Quite Low
intrathecal 1 38.92 Quite Low
nociceptor 1 25.00 Low Low
Disease Link Frequency Relevance Heat
Nociception 5 98.76 Very High Very High Very High
Pain 2 74.24 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In western blotting analysis, inhibiting M3G-induced nociceptive response using these inhibitors resulted in a significant blockade of ERK activation induced by M3G in the spinal cord.
M3G Positive_regulation (activation) of ERK in spinal cord associated with nociception and spinal cord
1) Confidence 0.15 Published 2009 Journal Biochem. Pharmacol. Section Abstract Doc Link 19589334 Disease Relevance 0.41 Pain Relevance 0.41

General Comments

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