INT161528

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Context Info
Confidence 0.64
First Reported 2009
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 1.27
Pain Relevance 0.38

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (Tnfaip8)
Anatomy Link Frequency
THP-1 1
Tnfaip8 (Mus musculus)
Pain Link Frequency Relevance Heat
cytokine 37 72.84 Quite High
Inflammation 6 69.04 Quite High
cINOD 1 54.40 Quite High
Inflammatory response 4 48.00 Quite Low
chemokine 5 5.00 Very Low Very Low Very Low
Pain 2 5.00 Very Low Very Low Very Low
Arthritis 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Injury 6 91.20 High High
Communicable Diseases 3 88.04 High High
Necrosis 1 81.28 Quite High
Cancer 1 80.92 Quite High
Sprains And Strains 62 75.00 Quite High
INFLAMMATION 9 69.04 Quite High
Pneumonia 1 62.20 Quite High
Enteropathy 2 55.20 Quite High
Apoptosis 3 51.64 Quite High
Infection 55 50.00 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The biological relevance of Tnfaip8 and Seh1l is strengthened by several key observations.
Localization (relevance) of Tnfaip8
1) Confidence 0.64 Published 2010 Journal PLoS Pathogens Section Body Doc Link PMC2932726 Disease Relevance 0.34 Pain Relevance 0.29
Both L-lactic acid and LcS culture supernatant containing 10 mM lactic acid inhibited NF-kappaB activation and increases in TNF-alpha mRNA expression and TNF-alpha protein secretion in THP-1 cells treated with LPS.
Localization (secretion) of TNF-alpha protein in THP-1
2) Confidence 0.01 Published 2009 Journal Am. J. Physiol. Gastrointest. Liver Physiol. Section Abstract Doc Link 19589943 Disease Relevance 0.93 Pain Relevance 0.09

General Comments

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