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Context Info
Confidence 0.32
First Reported 2008
Last Reported 2009
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 1.36
Pain Relevance 0.36

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (PTX3)
Anatomy Link Frequency
spinal 1
PTX3 (Homo sapiens)
Pain Link Frequency Relevance Heat
midbrain 5 100.00 Very High Very High Very High
dexamethasone 1 93.52 High High
cINOD 1 87.20 High High
Inflammation 3 78.88 Quite High
cytokine 1 72.44 Quite High
Spinal cord 6 72.24 Quite High
Inflammatory response 2 65.56 Quite High
Dopamine 9 26.92 Quite Low
gABA 8 22.68 Low Low
Central nervous system 7 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Rheumatoid Arthritis 21 99.00 Very High Very High Very High
Apoptosis 9 96.72 Very High Very High Very High
INFLAMMATION 5 86.96 High High
Autoimmune Disease 1 79.80 Quite High
Necrosis 1 70.72 Quite High
Disease 4 5.00 Very Low Very Low Very Low
Targeted Disruption 1 5.00 Very Low Very Low Very Low
Frailty 1 5.00 Very Low Very Low Very Low
Injury 1 5.00 Very Low Very Low Very Low
Neurodegenerative Disease 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The neural progenitors acquired a spinal positional identity because the RA treatment completely suppressed or significantly downregulated the rostral markers RX, BF1, GBX2 as well as midbrain dopaminergic markers PTX3, PAX2, NURR1, LMX1B, and TH (Figures 4E and 4F).
Negative_regulation (downregulated) of PTX3 in spinal associated with rheumatoid arthritis and midbrain
1) Confidence 0.32 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2346555 Disease Relevance 0.34 Pain Relevance 0.12
Our results eliminate a role for a number of potential opsonins, including complement, pentraxin-3, and fibronectin.
Negative_regulation (number) of pentraxin-3
2) Confidence 0.18 Published 2009 Journal J. Immunol. Section Abstract Doc Link 19597001 Disease Relevance 1.02 Pain Relevance 0.24

General Comments

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