INT161653

Context Info Confidence 0.04 First Reported 2009 Last Reported 2009 Negated 0 Speculated 0 Reported most in Abstract Documents 1 Total Number 1 Disease Relevance 1.05 Pain Relevance 0.46

cytoplasm (Gsr, Ifih1) mitochondrion (Gsr) intracellular (Ifih1) helicase activity (Ifih1) DNA binding (Ifih1) cytosol (Gsr)

Anatomy Link Frequency paw 2 Gsr (Mus musculus) Ifih1 (Mus musculus)

Pain Link Frequency Relevance Heat Inflammation 7 99.30 Analgesic 5 95.52 Pain 2 25.00

Disease Link Frequency Relevance Heat Cancer 2 100.00 Necrosis 2 100.00 INFLAMMATION 7 99.30 Pressure And Volume Under Development 5 98.76

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

In order to study the anti-inflammatory mechanism of MDT, we detected the activities of glutathione peroxidase (GPx) and glutathione reductase (GRd) in the liver, the levels of interleukin-1beta (IL-1beta), tumor necrosis factor (TNF-alpha), malondialdehyde (MDA) and nitric oxide (NO) in the edema paw tissue.

glutathione reductase Regulation (activities) of Gene_expression (levels) of MDA in paw associated with pressure and volume under development, necrosis, inflammation and cancer

1) Confidence 0.04 Published 2009 Journal Am. J. Chin. Med. Section Abstract Doc Link 19606516 Disease Relevance 1.05 Pain Relevance 0.46

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