INT161839

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Context Info
Confidence 0.47
First Reported 2005
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.47
Pain Relevance 0.14

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Tnfrsf11b) extracellular space (Tnfrsf11b) extracellular region (Tnfrsf11b)
proteinaceous extracellular matrix (Tnfrsf11b) extracellular matrix organization (Tnfrsf11b)
Anatomy Link Frequency
condyles 2
Tnfrsf11b (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Snapping jaw 2 75.00 Quite High
anesthesia 1 5.00 Very Low Very Low Very Low
complementary and alternative medicine 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Osteoporosis 24 97.32 Very High Very High Very High
Stress 1 80.52 Quite High
Temporomandibular Joint Syndrome 2 75.00 Quite High
Hypercalcemia 4 30.00 Quite Low
Postmenopausal Osteoporosis 2 10.64 Low Low
Body Weight 3 5.00 Very Low Very Low Very Low
Bone Cancer 3 5.00 Very Low Very Low Very Low
Endometriosis (extended) 3 5.00 Very Low Very Low Very Low
Gonadal Disease 1 5.00 Very Low Very Low Very Low
Disease 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In addition, bone mineral density (BMD) and osteoprotegerin expression in extracted-side condyles were significantly increased while osteoclast numbers were significantly decreased when compared with intact-side condyles.
Positive_regulation (increased) of Gene_expression (expression) of osteoprotegerin in condyles
1) Confidence 0.47 Published 2009 Journal Eur. J. Oral Sci. Section Abstract Doc Link 19627347 Disease Relevance 0.16 Pain Relevance 0.14
As shown in Fig. 5A, HEP extract significantly increased OPG mRNA expression in UMR 106 cells in a dose-dependent manner (P < 0.01).
Positive_regulation (increased) of Gene_expression (expression) of OPG mRNA
2) Confidence 0.31 Published 2005 Journal Evidence-based Complementary and Alternative Medicine Section Body Doc Link PMC1193542 Disease Relevance 0.31 Pain Relevance 0

General Comments

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