INT16188

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Context Info
Confidence 0.19
First Reported 1991
Last Reported 2008
Negated 0
Speculated 0
Reported most in Abstract
Documents 4
Total Number 4
Disease Relevance 3.07
Pain Relevance 2.85

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

molecular_function (Pls1) cellular_component (Pls1) biological_process (Pls1)
cytoplasm (Pls1)
Anatomy Link Frequency
paw 1
Phr 1
Pls1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
tetrodotoxin 19 100.00 Very High Very High Very High
Pain 13 99.56 Very High Very High Very High
ischemia 4 99.48 Very High Very High Very High
Arthritis 6 98.96 Very High Very High Very High
Lasting pain 1 90.24 High High
Inflammatory response 1 82.56 Quite High
antagonist 3 79.68 Quite High
cINOD 3 75.00 Quite High
Inflammation 3 69.92 Quite High
anesthesia 1 25.00 Low Low
Disease Link Frequency Relevance Heat
Complex Regional Pain Syndromes 3 100.00 Very High Very High Very High
Disorder Of Lipid Metabolism 2 100.00 Very High Very High Very High
Pain 13 99.56 Very High Very High Very High
Cv Unclassified Under Development 4 99.48 Very High Very High Very High
Reperfusion Injury 1 99.12 Very High Very High Very High
Experimental Arthritis 5 98.96 Very High Very High Very High
Nociception 6 98.02 Very High Very High Very High
Hypoxia 7 94.40 High High
Hypersensitivity 5 87.64 High High
INFLAMMATION 6 82.56 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Integrated peak Phr or Xs1 I and Xphar E activities remained augmented during respiratory inhibition.
Positive_regulation (augmented) of Xs1 I in Phr
1) Confidence 0.19 Published 1991 Journal Jpn. J. Physiol. Section Abstract Doc Link 1806672 Disease Relevance 0.49 Pain Relevance 0
TTX-S could be activated by step depolarizations positive to -60 mV, while TTX-I could be activated at potentials positive to -40 mV.
Positive_regulation (activated) of TTX-I associated with tetrodotoxin
2) Confidence 0.14 Published 1995 Journal Pflugers Arch. Section Abstract Doc Link 9026782 Disease Relevance 0 Pain Relevance 1.58
We investigated the parallels between the nociceptive and vascular sensitivity to NE in rats with chronic post-ischemia pain (CPIP), an animal model of CRPS-I induced by hind paw ischemia-reperfusion injury.
Positive_regulation (induced) of CRPS-I in paw associated with complex regional pain syndromes, nociception, pain, reperfusion injury and ischemia
3) Confidence 0.07 Published 2008 Journal Pain Section Abstract Doc Link 18079061 Disease Relevance 1.74 Pain Relevance 0.91
The effect of adjuvant arthritis (AA) on the pattern of rat serum proteins includes the upregulation of haptoglobin, orosomucoid, alpha2-macroglobulin, serine protease inhibitor-3, thiostatin, alpha1-antitrypsin, C-reactive protein, and the downregulation of kallikrein-binding protein, alpha1-inhibitor III, apolipoprotein A-I, alpha2-HS-glycoprotein, albumin, apolipoprotein A-IV, transthyretin and transferrin.
Positive_regulation (upregulation) of A-I associated with experimental arthritis, disorder of lipid metabolism and arthritis
4) Confidence 0.01 Published 2000 Journal Electrophoresis Section Abstract Doc Link 10892728 Disease Relevance 0.85 Pain Relevance 0.36

General Comments

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