INT161917

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Context Info
Confidence 0.01
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 0.89

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (POMC, Oprd1) small molecule metabolic process (POMC) signal transducer activity (Oprd1)
cell-cell signaling (POMC) extracellular space (POMC) generation of precursor metabolites and energy (POMC)
POMC (Homo sapiens)
Oprd1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Enkephalin 3 100.00 Very High Very High Very High
opioid receptor 2 100.00 Very High Very High Very High
mu opioid receptor 1 98.40 Very High Very High Very High
agonist 1 96.44 Very High Very High Very High
Antinociceptive 1 88.64 High High
anticonvulsant 2 87.04 High High
Neuropeptide 1 83.56 Quite High
Opioid 3 83.04 Quite High
Potency 1 78.16 Quite High
antagonist 1 66.00 Quite High
Disease Link Frequency Relevance Heat
Convulsion 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Molecular modeling suggested that the decrease of the affinity of Met-enkephalin to delta-opioid receptor could be accounted for by the loss of a single hydrogen bond.
Negative_regulation (decrease) of Met-enkephalin Binding (affinity) of opioid receptor associated with opioid receptor and enkephalin
1) Confidence 0.01 Published 2009 Journal ACS Chem. Biol. Section Abstract Doc Link 19634861 Disease Relevance 0 Pain Relevance 0.89

General Comments

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