INT161950

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Context Info
Confidence 0.23
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 1.01
Pain Relevance 0.72

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

aging (TGFBR1, Ngf) signal transduction (TGFBR1, Ngf) embryo development (TGFBR1)
extracellular space (Ngf) extracellular region (Ngf) cell motility (TGFBR1)
Anatomy Link Frequency
PSC 2
TGFBR1 (Homo sapiens)
Ngf (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Nerve growth factor 11 100.00 Very High Very High Very High
fibrosis 1 77.20 Quite High
Pain 2 76.08 Quite High
nociceptor 1 74.00 Quite High
Disease Link Frequency Relevance Heat
Primary Sclerosing Cholangitis 6 95.96 Very High Very High Very High
Cirrhosis 3 93.48 High High
Apoptosis 1 81.12 Quite High
Pancreatic Cancer 1 78.48 Quite High
Pain 2 76.08 Quite High
Fibrosis 1 5.00 Very Low Very Low Very Low
Wound Healing 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
NGF secretion was diminished by the activin-like kinase (ALK)-5 inhibitor SB431542, indicating the predominant role of ALK5 in activating the NGF system in PSC.
activin-like kinase Negative_regulation (diminished) of Localization (secretion) of NGF in PSC associated with nerve growth factor and primary sclerosing cholangitis
1) Confidence 0.23 Published 2009 Journal Growth Factors Section Abstract Doc Link 19639490 Disease Relevance 1.01 Pain Relevance 0.72

General Comments

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