INT161995

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.06
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 2
Disease Relevance 0.33
Pain Relevance 1.28

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Ctu2) molecular_function (Ctu2) protein complex (Ctu2)
cellular_component (Ctu2) biological_process (Ctu2) cytoplasm (Ctu2)
Anatomy Link Frequency
brain 1
Ctu2 (Rattus norvegicus)
Fbxo23 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
cINOD 8 95.92 Very High Very High Very High
Inflammation 4 93.20 High High
diclofenac 6 92.32 High High
gABA 4 84.28 Quite High
Neurotransmitter 2 74.76 Quite High
Disease Link Frequency Relevance Heat
INFLAMMATION 4 93.20 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The active metabolite of fenbufen, 4-biphenylacetic acid inhibited [(3)H]NCS-382 binding with a twofold higher affinity than GHB.
NCS-382 Binding (binding) of GHB
1) Confidence 0.06 Published 2009 Journal Fundam Clin Pharmacol Section Abstract Doc Link 19645815 Disease Relevance 0.16 Pain Relevance 0.66
When measured in a rat brain homogenate [(3)H]NCS-382 binding assay, gamma-hydroxyfenbufen inhibited [(3)H]NCS-382 binding with a 10-fold higher affinity than GHB (K(i) 0.44 microM), thus establishing it as a novel lead structure.
NCS-382 Binding (binding) of GHB in brain
2) Confidence 0.06 Published 2009 Journal Fundam Clin Pharmacol Section Abstract Doc Link 19645815 Disease Relevance 0.17 Pain Relevance 0.62

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox