INT162006

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Context Info
Confidence 0.44
First Reported 2007
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 7
Total Number 7
Disease Relevance 3.30
Pain Relevance 0.13

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (ASAP1) cytoplasm (ASAP1)
Anatomy Link Frequency
plasma 4
bladder 2
ASAP1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Pain 2 65.32 Quite High
Angina 3 61.48 Quite High
interstitial cystitis 4 50.00 Quite Low
cva 3 13.32 Low Low
cytokine 9 5.00 Very Low Very Low Very Low
aspirin 2 5.00 Very Low Very Low Very Low
anesthesia 2 5.00 Very Low Very Low Very Low
imagery 2 5.00 Very Low Very Low Very Low
complementary and alternative medicine 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Pulmonary Alveolar Proteinosis 103 100.00 Very High Very High Very High
Cv General 2 Under Development 92 100.00 Very High Very High Very High
Pulmonary Hypertension 14 100.00 Very High Very High Very High
Overweight 2 94.72 High High
Nicotine Addiction 1 94.16 High High
Congenital Anomalies 9 92.96 High High
Pneumothorax 4 87.56 High High
Hemorrhage 3 76.08 Quite High
Bronchitis 1 70.60 Quite High
Cancer 11 67.44 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
One woman who last had a Pap test 14 years ago noted,
Positive_regulation (had) of Gene_expression (test) of Pap
1) Confidence 0.44 Published 2007 Journal Prev Chronic Dis Section Body Doc Link PMC2099293 Disease Relevance 0.39 Pain Relevance 0.07
CONCLUSIONS: Urinary HIP/PAP levels were significantly higher in IC patients and the apparent HIP/PAP expression in the bladder urothelium was more frequently observed among IC patients.
Positive_regulation (higher) of Gene_expression (levels) of PAP in bladder
2) Confidence 0.37 Published 2010 Journal Urology Section Body Doc Link 19646740 Disease Relevance 0.07 Pain Relevance 0
In this study, we showed that (1) plasma ANP concentrations were elevated in patients with ASD regardless of the presence of PAH, (2) plasma ANP concentrations were correlated positively with PAP, RVEDV and RVESV; and correlated negatively with RVEF, and (3) after transcatheter closure of ASD, plasma ANP concentrations were markedly decreased, the RVEDV, RVESV decreased and the RVEF increased markedly.
Positive_regulation (positively) of Gene_expression (correlated) of PAP in plasma associated with pulmonary hypertension and cv general 2 under development
3) Confidence 0.25 Published 2008 Journal Cardiovasc Ultrasound Section Body Doc Link PMC2467405 Disease Relevance 0.55 Pain Relevance 0
In this study, we showed that (1) plasma ANP concentrations were elevated in patients with ASD regardless of the presence of PAH, (2) plasma ANP concentrations were correlated positively with PAP, RVEDV and RVESV; and correlated negatively with RVEF, and (3) after transcatheter closure of ASD, plasma ANP concentrations were markedly decreased, the RVEDV, RVESV decreased and the RVEF increased markedly.
Positive_regulation (elevated) of Gene_expression (correlated) of PAP in plasma associated with pulmonary hypertension and cv general 2 under development
4) Confidence 0.25 Published 2008 Journal Cardiovasc Ultrasound Section Body Doc Link PMC2467405 Disease Relevance 0.61 Pain Relevance 0
At the same time, also the CT scan showed a marked improvement of PAP appearance, although the crazy paving pattern persisted (Figure 2B).


Positive_regulation (improvement) of Gene_expression (appearance) of PAP associated with pulmonary alveolar proteinosis
5) Confidence 0.21 Published 2010 Journal Orphanet J Rare Dis Section Body Doc Link PMC2999609 Disease Relevance 0.59 Pain Relevance 0.06
These are the first results to demonstrate familial primary PAP in humans and that GM-CSF-R?
Positive_regulation (primary) of Gene_expression (humans) of PAP associated with pulmonary alveolar proteinosis
6) Confidence 0.12 Published 2008 Journal The Journal of Experimental Medicine Section Body Doc Link PMC2585845 Disease Relevance 0.55 Pain Relevance 0
These are the first results to demonstrate familial primary PAP in humans and that GM-CSF-R?
Positive_regulation (familial) of Gene_expression (humans) of PAP associated with pulmonary alveolar proteinosis
7) Confidence 0.12 Published 2008 Journal The Journal of Experimental Medicine Section Body Doc Link PMC2585845 Disease Relevance 0.55 Pain Relevance 0

General Comments

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