INT162042

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Context Info
Confidence 0.17
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 1.17
Pain Relevance 0.31

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (F2, OSM) extracellular region (F2, OSM) cell proliferation (OSM)
peptidase activity (F2) plasma membrane (F2)
Anatomy Link Frequency
macrophages 1
F2 (Homo sapiens)
OSM (Homo sapiens)
Pain Link Frequency Relevance Heat
cytokine 1 99.32 Very High Very High Very High
Inflammation 7 95.36 Very High Very High Very High
Angina 1 92.64 High High
Disease Link Frequency Relevance Heat
Increased Venous Pressure Under Development 5 98.48 Very High Very High Very High
INFLAMMATION 5 95.36 Very High Very High Very High
Myocardial Infarction 2 94.60 High High
Cv General 3 Under Development 1 92.64 High High
Stroke 1 91.96 High High
Disease 1 86.28 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We show that the coagulation enzyme thrombin up-regulates oncostatin M (OSM), a pleiotropic cytokine implicated in the pathophysiology of vascular disease, in human monocyte-derived macrophages (MDMs) up to 16.8-fold.
thrombin Regulation (regulates) of OSM in macrophages associated with increased venous pressure under development and cytokine
1) Confidence 0.17 Published 2009 Journal Blood Section Abstract Doc Link 19652200 Disease Relevance 1.17 Pain Relevance 0.31

General Comments

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