INT162071

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Context Info
Confidence 0.41
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Title
Documents 1
Total Number 1
Disease Relevance 0.34
Pain Relevance 0.82

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (MC1R, TNF) pigmentation (MC1R) signal transduction (TNF)
extracellular space (TNF) extracellular region (TNF) intracellular (TNF)
Anatomy Link Frequency
keratinocytes 3
MC1R (Homo sapiens)
TNF (Homo sapiens)
Pain Link Frequency Relevance Heat
melanocortin 1 receptor 9 97.60 Very High Very High Very High
Inflammatory response 1 93.48 High High
Inflammation 2 83.00 Quite High
Disease Link Frequency Relevance Heat
INFLAMMATION 3 93.48 High High
Cancer 1 80.56 Quite High
Necrosis 1 80.32 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Constitutive expression of MC1R in HaCaT keratinocytes inhibits basal and UVB-induced TNF-alpha production.
Gene_expression (expression) of MC1R in keratinocytes Negative_regulation (inhibits) of Gene_expression (production) of TNF-alpha in keratinocytes
1) Confidence 0.41 Published 2009 Journal Photochem. Photobiol. Section Title Doc Link 19656324 Disease Relevance 0.34 Pain Relevance 0.82

General Comments

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