INT16214

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.74
First Reported 1989
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 36
Total Number 36
Disease Relevance 21.80
Pain Relevance 4.87

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (F13A1) transferase activity, transferring acyl groups (F13A1) cytoplasm (F13A1)
Anatomy Link Frequency
platelets 2
plasma 1
brain 1
external 1
fibroblasts 1
F13A1 (Homo sapiens)
Pain Link Frequency Relevance Heat
lidocaine 5 100.00 Very High Very High Very High
Pain 31 99.92 Very High Very High Very High
abdominal pain 2 99.44 Very High Very High Very High
Inflammation 97 98.76 Very High Very High Very High
corticosteroid 5 98.64 Very High Very High Very High
ischemia 28 98.60 Very High Very High Very High
imagery 155 97.24 Very High Very High Very High
Percutaneous transluminal coronary angioplasty 7 96.32 Very High Very High Very High
Demyelination 47 96.08 Very High Very High Very High
topical agent 2 93.80 High High
Disease Link Frequency Relevance Heat
Injury 522 99.98 Very High Very High Very High
Coagulation Disorder 90 99.92 Very High Very High Very High
Pain 22 99.92 Very High Very High Very High
Renal Failure 15 99.84 Very High Very High Very High
Peritonitis 10 99.72 Very High Very High Very High
Ulcers 130 99.68 Very High Very High Very High
Abdominal Pain 2 99.44 Very High Very High Very High
Thrombosis 171 99.12 Very High Very High Very High
Atherosclerosis 105 98.98 Very High Very High Very High
Pressure And Volume Under Development 14 98.94 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
However, a final question arises -mainly theoretically- when coming to fibrin glue application: autologous or commercial?
Localization (application) of fibrin
1) Confidence 0.74 Published 2010 Journal BMC Gastroenterol Section Body Doc Link PMC2829488 Disease Relevance 0.75 Pain Relevance 0.16
[Experience in fibrin glue application for the treatment of non-formed fistulas of the gastrointestinal tract].
Localization (application) of fibrin associated with fistula
2) Confidence 0.67 Published 2006 Journal Khirurgiia (Mosk) Section Title Doc Link 17047628 Disease Relevance 0.43 Pain Relevance 0.08
At 2 hours of ischemia, there was edema of the submucosa and lamina propria attributable to accumulation of platelets, fibrin, and neutrophils in capillaries of the lamina propria.
Localization (accumulation) of fibrin in lamina associated with pressure and volume under development and ischemia
3) Confidence 0.65 Published 1995 Journal Vet. Pathol. Section Abstract Doc Link 7604495 Disease Relevance 0.76 Pain Relevance 0.42
SK probably releases fibrin clot containing bacteria, leukocytes and debris from the colonized catheter into the peritoneal cavity causing a "peritonitis-like syndrome" of 1 to 3 days duration.
Localization (releases) of fibrin in peritoneal cavity associated with syndrome and peritonitis
4) Confidence 0.65 Published 1991 Journal Clin. Nephrol. Section Abstract Doc Link 2007292 Disease Relevance 0.97 Pain Relevance 0.10
Autopsy demonstrated diffuse and extensive distal coronary arterial embolization of grumous material, including cholesterol crystals, platelets, and fibrin.
Localization (embolization) of fibrin in platelets
5) Confidence 0.60 Published 1991 Journal Clin Cardiol Section Abstract Doc Link 1810686 Disease Relevance 0.41 Pain Relevance 0.43
Intracatheter streptokinase (SK) is advocated as effective treatment with minimal adverse effects in both recurrent bacterial peritonitis and catheter fibrin blockage in continuous ambulatory peritoneal dialysis (CAPD) patients.
Localization (blockage) of fibrin associated with renal failure and peritonitis
6) Confidence 0.60 Published 1991 Journal Clin. Nephrol. Section Abstract Doc Link 2007292 Disease Relevance 0.88 Pain Relevance 0.08
Our investigation focused on the control of the parameter changes important for ulcer healing: wound surface area, wound appearance (fibrin accumulations, exudation, granulation, and epithelization), ulcer surroundings and associated symptoms.
Localization (appearance) of fibrin in granulation associated with injury and ulcers
7) Confidence 0.60 Published 2008 Journal Arch. Dermatol. Res. Section Abstract Doc Link 18629524 Disease Relevance 1.29 Pain Relevance 0.39
Fibrin tissue bioadhesives which mimics the natural fibrinogen and thrombin reaction are used on various ophthalmologic surgeries for tissue adhesion, blood coagulation and wound healing.12-18 The use of tissue bioadhesives as an alternative means of attaching the grafts may shorten operating time, improve postoperative discomfort, and possibly avoid suture-related complications.16-18
Localization (reaction) of Fibrin in blood associated with wound healing and adhesions
8) Confidence 0.55 Published 2008 Journal Korean Journal of Ophthalmology : KJO Section Body Doc Link PMC2629906 Disease Relevance 1.02 Pain Relevance 0.09
Relief of post-tonsillectomy pain by release of lidocaine from fibrin glue.
Localization (release) of fibrin associated with pain and lidocaine
9) Confidence 0.31 Published 2001 Journal Laryngoscope Section Title Doc Link 11359133 Disease Relevance 0.20 Pain Relevance 0.49
Local haemostatic agents include collagen, gelatin or cellulose-based products, fibrin and synthetic glues or adhesives that can be used for both external and internal bleeding while polysaccharide-based and inorganic haemostatics are still mainly used and approved for external bleeding.
Localization (used) of fibrin in internal associated with hemorrhage
10) Confidence 0.15 Published 2010 Journal Crit Care Section Body Doc Link PMC2887168 Disease Relevance 0.75 Pain Relevance 0.09
The principle of the contrast agent is that it is targeted to fibrin.
Localization (targeted) of fibrin
11) Confidence 0.13 Published 2007 Journal Eur J Nucl Med Mol Imaging Section Body Doc Link PMC1914271 Disease Relevance 0.72 Pain Relevance 0.48
In our study, LPS caused the disappearance of Factor XIII (spot V).
Localization (disappearance) of Factor XIII
12) Confidence 0.12 Published 2008 Journal Proteome Sci Section Body Doc Link PMC2413206 Disease Relevance 0.09 Pain Relevance 0.03
Elevated plasma D-dimer levels indicate increased plasmin degradation of cross-linked fibrin, and are therefore an indirect indication of increased thrombin activity and fibrin formation.
Localization (formation) of fibrin in plasma
13) Confidence 0.08 Published 1989 Journal Haemostasis Section Abstract Doc Link 2731776 Disease Relevance 0.30 Pain Relevance 0.22
In this study, we used fibrin binding sequences of FN as DBB coating material; therefore, the RGD sequence of FN is not included and results of the initial healing stage, that is, post-surgery 2 weeks, were not included.
Localization (sequences) of fibrin
14) Confidence 0.08 Published 2010 Journal Journal of Periodontal & Implant Science Section Body Doc Link PMC2967808 Disease Relevance 0.33 Pain Relevance 0
The alternative 'Trap' hypothesis proposes that fibrin and macromolecules eventually leak into the dermis where they bind with growth factors, making then unavailable for the tissue repair process.
Localization (leak) of fibrin in dermis
15) Confidence 0.08 Published 2010 Journal Trials Section Body Doc Link PMC2847559 Disease Relevance 2.11 Pain Relevance 0.04
Is autologous fibrin effective in grafting dMSCs?
Localization (autologous) of fibrin
16) Confidence 0.07 Published 2009 Journal Yonsei Medical Journal Section Body Doc Link PMC2796411 Disease Relevance 0.23 Pain Relevance 0
It is also proposed that fibroblasts from the chronic wounds migrate into the fibrin deposit; secrete ECM proteins causing wound contraction and scar formation [11].
Localization (secrete) of fibrin in fibroblasts associated with cicatrix and injury
17) Confidence 0.07 Published 2005 Journal Reprod Biol Endocrinol Section Body Doc Link PMC548295 Disease Relevance 1.29 Pain Relevance 0.16
Tumor cells can either directly activate the blood clotting system or indirectly stimulate mononuclear cells to synthesize and express various procoagulants, subsequently leading to prothrombin activation, fibrin formation, and generation of a thrombus.
Localization (formation) of fibrin in mononuclear cells associated with coagulation disorder, cancer and thrombosis
18) Confidence 0.07 Published 1999 Journal Semin. Thromb. Hemost. Section Abstract Doc Link 10357083 Disease Relevance 1.76 Pain Relevance 0.13
We sought to determine where activated factor X (FXa), (pro)thrombin, and fibrin(ogen) are localized in thrombi formed under venous shear.


Localization (localized) of fibrin
19) Confidence 0.06 Published 2010 Journal PLoS ONE Section Abstract Doc Link PMC2861630 Disease Relevance 0.06 Pain Relevance 0
Fluorescence microscopy was used to study the accumulation of platelets, FXa, (pro)thrombin, and fibrin(ogen) in thrombi formed in vitro and in vivo.
Localization (accumulation) of fibrin in platelets
20) Confidence 0.06 Published 2010 Journal PLoS ONE Section Abstract Doc Link PMC2861630 Disease Relevance 0.13 Pain Relevance 0

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox