INT162165

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Context Info
Confidence 0.50
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 2
Disease Relevance 0
Pain Relevance 1.25

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Golgi apparatus (PLD2) plasma membrane (PLD2) nucleus (PLD2)
cytoskeleton organization (PLD2)
WDTC1 (Homo sapiens)
PLD2 (Homo sapiens)
Pain Link Frequency Relevance Heat
Opioid 8 99.72 Very High Very High Very High
opioid receptor 24 99.04 Very High Very High Very High
tolerance 4 94.68 High High
agonist 4 49.68 Quite Low

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Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
It has been further demonstrated, that the opioid-mediated and ADP-ribosylation factor (ARF)-dependent activation of phospholipase D2 (PLD2) is a prerequisite for MOPr endocytosis.
ADP Positive_regulation (activation) of phospholipase D2 associated with opioid receptor and opioid
1) Confidence 0.50 Published 2009 Journal Cell. Signal. Section Abstract Doc Link 19666113 Disease Relevance 0 Pain Relevance 0.62
It has been further demonstrated, that the opioid-mediated and ADP-ribosylation factor (ARF)-dependent activation of phospholipase D2 (PLD2) is a prerequisite for MOPr endocytosis.
ADP Positive_regulation (activation) of PLD2 associated with opioid receptor and opioid
2) Confidence 0.50 Published 2009 Journal Cell. Signal. Section Abstract Doc Link 19666113 Disease Relevance 0 Pain Relevance 0.62

General Comments

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