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Context Info
Confidence 0.38
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 0.94

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (ARF6) endosome (ARF6) Golgi apparatus (ARF6)
intracellular (ARF6) GTPase activity (ARF6) cytoplasm (ARF6)
ARF6 (Homo sapiens)
Pain Link Frequency Relevance Heat
agonist 2 99.96 Very High Very High Very High
opioid receptor 12 98.68 Very High Very High Very High
Opioid 4 91.20 High High
tolerance 2 70.28 Quite High


Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We also found that expression of an effector domain mutant of ARF6, which is incapable of activating PLD, blocked agonist-induced endocytosis suggesting that ARF6 function in MOPr trafficking is PLD2-mediated.
Negative_regulation (blocked) of Gene_expression (expression) of ARF6 associated with agonist and opioid receptor
1) Confidence 0.38 Published 2009 Journal Cell. Signal. Section Abstract Doc Link 19666113 Disease Relevance 0 Pain Relevance 0.94

General Comments

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