INT162215

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Context Info
Confidence 0.18
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0.19
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (Tnfrsf4)
Anatomy Link Frequency
spinal 4
Tnfrsf4 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Neuropathic pain 4 50.00 Quite Low
Perioperative pain 4 50.00 Quite Low
Pain 4 10.00 Low Low
Spinal cord 4 5.00 Very Low Very Low Very Low
Peripheral nerve injury 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Neuropathic Pain 4 72.20 Quite High
Hypersensitivity 8 69.16 Quite High
Post Operative Pain 4 50.00 Quite Low
Nervous System Injury 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
RESULTS: In the postoperative pain model, minocycline did not suppress mechanical hypersensitivity, but did inhibit an increase in spinal OX42 expression.
Positive_regulation (increase) of Gene_expression (expression) of OX42 in spinal
1) Confidence 0.18 Published 2009 Journal Anesthesiology Section Body Doc Link 19672178 Disease Relevance 0.14 Pain Relevance 0
CONCLUSIONS: The results of the present study suggest that spinal OX42 expression has a more important role in the development of neuropathic pain than in postoperative pain, and that an increase in spinal OX42 expression does not contribute to postoperative mechanical hypersensitivity.


Positive_regulation (increase) of Gene_expression (expression) of OX42 in spinal
2) Confidence 0.18 Published 2009 Journal Anesthesiology Section Body Doc Link 19672178 Disease Relevance 0.05 Pain Relevance 0

General Comments

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