INT162225

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.09
First Reported 2005
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 5
Disease Relevance 1.46
Pain Relevance 1.07

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
endothelial cells 1
TMJ 1
astrocytes 1
cx (Mus musculus)
Pain Link Frequency Relevance Heat
Trigeminal ganglion neurons 2 99.04 Very High Very High Very High
Inflammatory stimuli 2 98.36 Very High Very High Very High
qutenza 5 96.68 Very High Very High Very High
Inflammation 11 94.04 High High
Pain 1 93.36 High High
Snapping jaw 3 92.88 High High
trigeminal ganglion 1 59.84 Quite High
fibrosis 20 55.68 Quite High
fifth nerve 1 54.20 Quite High
imagery 4 42.68 Quite Low
Disease Link Frequency Relevance Heat
Ganglion Cysts 3 98.88 Very High Very High Very High
INFLAMMATION 11 98.36 Very High Very High Very High
Glioma 4 94.20 High High
Pain 1 93.36 High High
Temporomandibular Joint Syndrome 3 92.88 High High
Arthritis 2 75.00 Quite High
Inborn Genetic Diseases 4 57.84 Quite High
Cystic Fibrosis 20 56.24 Quite High
Disease 4 30.32 Quite Low
Injury 8 21.80 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Thus, trigeminal ganglion neurons and satellite glia can differentially regulate Cx expression in response to the type and duration of inflammatory stimuli, which likely facilitates increased neuron-glia communication during acute and chronic inflammation and pain in the TMJ.
Gene_expression (expression) of Cx in TMJ associated with ganglion cysts, pain, snapping jaw, inflammation, inflammatory stimuli and trigeminal ganglion neurons
1) Confidence 0.09 Published 2008 Journal Neuron Glia Biol. Section Abstract Doc Link 19674505 Disease Relevance 0.96 Pain Relevance 1.02
Also, it must be noted that Cx overexpression was reported to be associated with altered expression of other genes [24].
Gene_expression (overexpression) of Cx
2) Confidence 0.04 Published 2005 Journal Purinergic Signal Section Body Doc Link PMC2096548 Disease Relevance 0.07 Pain Relevance 0
Thus, it is possible that Cx expression upregulates the activity of an ATP-releasing anion channel which is distinct from the Cx-hemichannel.
Gene_expression (expression) of Cx
3) Confidence 0.04 Published 2005 Journal Purinergic Signal Section Body Doc Link PMC2096548 Disease Relevance 0.24 Pain Relevance 0.06
Also, cells endogenously expressing Cx, such as astrocytes, endothelial cells and bronchial epithelial cells were shown to respond with ATP release to hemichannel stimulation by reduction of extracellular Ca2+ or mechanostress [16, 17, 19, 20].
Gene_expression (expressing) of Cx in astrocytes
4) Confidence 0.04 Published 2005 Journal Purinergic Signal Section Body Doc Link PMC2096548 Disease Relevance 0.09 Pain Relevance 0
Also, cells endogenously expressing Cx, such as astrocytes, endothelial cells and bronchial epithelial cells were shown to respond with ATP release to hemichannel stimulation by reduction of extracellular Ca2+ or mechanostress [16, 17, 19, 20].
Gene_expression (expressing) of Cx in endothelial cells
5) Confidence 0.01 Published 2005 Journal Purinergic Signal Section Body Doc Link PMC2096548 Disease Relevance 0.09 Pain Relevance 0

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox