INT162247

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Context Info
Confidence 0.09
First Reported 2006
Last Reported 2009
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 2.60
Pain Relevance 2.03

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

chromosome (Hist1h2aa) nucleus (Hist1h2aa) DNA binding (Hist1h2aa)
Anatomy Link Frequency
lymph nodes 1
Hist1h2aa (Rattus norvegicus)
Pain Link Frequency Relevance Heat
cytokine 18 99.96 Very High Very High Very High
Neuritis 12 98.88 Very High Very High Very High
aspirin 26 97.16 Very High Very High Very High
Inflammation 11 96.16 Very High Very High Very High
Sciatic nerve 2 88.88 High High
Neuropathic pain 1 83.40 Quite High
Demyelination 1 76.48 Quite High
Peripheral nervous system 1 56.08 Quite High
Glutamate 2 46.08 Quite Low
excitatory amino acid 1 45.68 Quite Low
Disease Link Frequency Relevance Heat
Experimental Autoimmune Neuritis 12 98.88 Very High Very High Very High
INFLAMMATION 17 96.16 Very High Very High Very High
Schizophrenia 36 89.76 High High
Hyperglycemia 1 84.40 Quite High
Neuropathic Pain 1 83.40 Quite High
Demyelinating Disease 3 76.48 Quite High
Paraparesis 1 70.68 Quite High
Necrosis 1 62.04 Quite High
Cancer 1 61.68 Quite High
Neuropathy 1 59.48 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
-interferon production) relative to TH-2 activity (e.g.
Positive_regulation (relative) of TH-2
1) Confidence 0.09 Published 2006 Journal Trials Section Body Doc Link PMC1626076 Disease Relevance 0.74 Pain Relevance 0.51
In lymph nodes of EAN rats, Compound A depressed Th1 and Th17 cytokines, but increased Th2 cytokine and Foxp3 expression.
Positive_regulation (increased) of Th2 in lymph nodes associated with neuritis and cytokine
2) Confidence 0.02 Published 2009 Journal J. Immunol. Section Abstract Doc Link 19675162 Disease Relevance 1.86 Pain Relevance 1.52

General Comments

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