INT162252

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Context Info
Confidence 0.36
First Reported 2009
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 4
Total Number 4
Disease Relevance 0.79
Pain Relevance 0.25

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transport (Slc40a1) plasma membrane (Slc40a1)
Anatomy Link Frequency
liver 1
lung 1
Slc40a1 (Mus musculus)
Pain Link Frequency Relevance Heat
Paracetamol 6 99.88 Very High Very High Very High
imagery 5 86.32 High High
fibrosis 7 62.88 Quite High
Inflammation 10 5.00 Very Low Very Low Very Low
anesthesia 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Paracoccidioidomycosis 25 100.00 Very High Very High Very High
Hepatotoxicity 9 99.14 Very High Very High Very High
Disease 5 76.36 Quite High
Mycoses 1 67.92 Quite High
Cancer 1 63.28 Quite High
Pulmonary Fibrosis 2 62.88 Quite High
Congenital Anomalies 2 50.00 Quite Low
Sprains And Strains 3 37.92 Quite Low
Chronic Disease 1 15.28 Low Low
Disease Progression 2 9.92 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In the microscopic studies, PCM induced toxicity showed haemorrhages, fatty changes and necrosis.
Positive_regulation (induced) of PCM
1) Confidence 0.36 Published 2009 Journal Indian J. Med. Res. Section Body Doc Link 19675387 Disease Relevance 0 Pain Relevance 0
This study was undertaken to evaluate the hepatoprotective activity of six commercially available formulations, namely Liv 52, Livergen, Livokin, Octogen, Stimuliv and Tefroliv in acute liver toxicity in mice model induced by paracetamol (PCM).
Positive_regulation (induced) of PCM in liver associated with paracetamol and hepatotoxicity
2) Confidence 0.36 Published 2009 Journal Indian J. Med. Res. Section Abstract Doc Link 19675387 Disease Relevance 0.26 Pain Relevance 0.17
INTERPRETATION & CONCLUSION: The present findings demonstrated the efficacy of polyherbal liquid formulations at two dose levels in PCM induced hepatotoxicity in mice.
Positive_regulation (induced) of PCM
3) Confidence 0.36 Published 2009 Journal Indian J. Med. Res. Section Body Doc Link 19675387 Disease Relevance 0 Pain Relevance 0
This study focus on a comparative analysis between high-resolution computed tomography (HRCT) and histopathological parameters, determining usefulness of performing noninvasive conventional medical X-ray tomography in the follow up of sequential lung lesions in the experimental PCM model induced in mice by conidial inoculation.


Positive_regulation (induced) of PCM in lung associated with paracoccidioidomycosis
4) Confidence 0.11 Published 2010 Journal PLoS Neglected Tropical Diseases Section Body Doc Link PMC2894136 Disease Relevance 0.53 Pain Relevance 0.07

General Comments

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