INT162253

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Context Info
Confidence 0.59
First Reported 2006
Last Reported 2010
Negated 2
Speculated 0
Reported most in Body
Documents 30
Total Number 33
Disease Relevance 20.16
Pain Relevance 7.18

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

protein folding (BAG3) cytosol (BAG3) plasma membrane (BAG3)
cytoplasm (BAG3)
Anatomy Link Frequency
brain 2
blood 1
plasma 1
anterior 1
posterior 1
BAG3 (Homo sapiens)
Pain Link Frequency Relevance Heat
cva 1925 100.00 Very High Very High Very High
Catecholamine 17 99.10 Very High Very High Very High
anesthesia 156 96.88 Very High Very High Very High
Electroencephalography 24 90.92 High High
epidural 31 85.80 High High
isoflurane 3 82.52 Quite High
cerebral cortex 60 79.88 Quite High
Central nervous system 4 75.96 Quite High
medulla 3 72.48 Quite High
ischemia 16 70.48 Quite High
Disease Link Frequency Relevance Heat
Cv General 3 Under Development 1871 100.00 Very High Very High Very High
Head Trauma 82 99.60 Very High Very High Very High
Brain Injury 365 99.56 Very High Very High Very High
Sleep Disorders 355 99.40 Very High Very High Very High
Injury 189 97.88 Very High Very High Very High
Unconsciousness 30 97.28 Very High Very High Very High
Coma 65 97.20 Very High Very High Very High
Cv Unclassified Under Development 17 97.16 Very High Very High Very High
Contusions 14 95.16 Very High Very High Very High
Sepsis 2 95.12 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Positive correlations were detected between BIS and rCBF values in dorsolateral prefontal, parietal, anterior and posterior cingulate, precuneal, mesiofrontal, mesiotemporal and insular cortices.
Gene_expression (detected) of BIS in parietal
1) Confidence 0.59 Published 2009 Journal Arch Ital Biol Section Abstract Doc Link 19678596 Disease Relevance 0 Pain Relevance 0.11
A review of the literature revealed only eight case reports of using BIS monitoring during CPR published in the last 6 years, but none described BIS monitoring in only one patient undergoing double cardiac resuscitation within a few days.


Gene_expression (monitoring) of BIS
2) Confidence 0.45 Published 2008 Journal Int J Emerg Med Section Body Doc Link PMC2657270 Disease Relevance 0.39 Pain Relevance 0
A review of the literature revealed only eight case reports of using BIS monitoring during CPR published in the last 6 years, but none described BIS monitoring in only one patient undergoing double cardiac resuscitation within a few days.


Gene_expression (monitoring) of BIS
3) Confidence 0.45 Published 2008 Journal Int J Emerg Med Section Body Doc Link PMC2657270 Disease Relevance 0.33 Pain Relevance 0
Other authors described BIS values above 40 as acceptable during CPR [3, 12].
Gene_expression (values) of BIS
4) Confidence 0.45 Published 2008 Journal Int J Emerg Med Section Body Doc Link PMC2657270 Disease Relevance 0.35 Pain Relevance 0
BIS, StcO2, ICP, and CPP are related, but distinct indices of outcome with severe brain injury.
Gene_expression (related) of BIS in brain associated with cva and brain injury
5) Confidence 0.43 Published 2006 Journal Crit Care Section Body Doc Link PMC1794465 Disease Relevance 1.39 Pain Relevance 0.58
The hourly StcO2 and BIS values did not influence treatment decisions.
Gene_expression (values) of BIS
6) Confidence 0.43 Published 2006 Journal Crit Care Section Body Doc Link PMC1794465 Disease Relevance 0.44 Pain Relevance 0.08
A frontal subdural hematoma may interfere with BIS or StcO2 values.
Gene_expression (values) of BIS associated with head trauma
7) Confidence 0.43 Published 2006 Journal Crit Care Section Body Doc Link PMC1794465 Disease Relevance 0.90 Pain Relevance 0.28
ICP, CPP, BIS and StcO2 rates are: ICP ?
Gene_expression (rates) of BIS associated with cva
8) Confidence 0.43 Published 2006 Journal Crit Care Section Body Doc Link PMC1794465 Disease Relevance 0.80 Pain Relevance 0.36
With a BIS <60 and StcO2 <70 an ICP monitor is indicated.
Gene_expression (<60) of BIS associated with cva
9) Confidence 0.43 Published 2006 Journal Crit Care Section Body Doc Link PMC1794465 Disease Relevance 1.94 Pain Relevance 0.57
With a BIS ?
Gene_expression (With) of BIS
10) Confidence 0.43 Published 2006 Journal Crit Care Section Body Doc Link PMC1794465 Disease Relevance 1.92 Pain Relevance 0.56
Surviving patients and patients with good neurological outcome have higher BIS and StcO2 values.
Gene_expression (values) of BIS
11) Confidence 0.43 Published 2006 Journal Crit Care Section Body Doc Link PMC1794465 Disease Relevance 1.18 Pain Relevance 0.55
The ICP, MAP, BIS, and StcO2 values were recorded hourly for each of the first six post-injury days.
Gene_expression (values) of BIS associated with injury and cva
12) Confidence 0.43 Published 2006 Journal Crit Care Section Body Doc Link PMC1794465 Disease Relevance 1.23 Pain Relevance 0.29
With a BIS ?
Gene_expression (With) of BIS
13) Confidence 0.43 Published 2006 Journal Crit Care Section Body Doc Link PMC1794465 Disease Relevance 1.54 Pain Relevance 0.49
With BIS ?
Gene_expression (With) of BIS
14) Confidence 0.43 Published 2006 Journal Crit Care Section Body Doc Link PMC1794465 Disease Relevance 0.91 Pain Relevance 0.42
Combined BIS and StcO2 rates are: BIS ?
Gene_expression (rates) of BIS
15) Confidence 0.43 Published 2006 Journal Crit Care Section Body Doc Link PMC1794465 Disease Relevance 0.89 Pain Relevance 0.42
The study purpose is to determine the relationships between StcO2 and BIS values in severe brain injury and ICU outcomes (survival, discharge Glasgow Coma Scale (GCS) score, ICP, CPP, and interventions to lower ICP).


Gene_expression (values) of BIS in brain associated with cva, coma and brain injury
16) Confidence 0.43 Published 2006 Journal Crit Care Section Body Doc Link PMC1794465 Disease Relevance 1.29 Pain Relevance 0.40
The noninvasive, A-2000 Bispectral Index XP Monitoring System (Aspect Medical Systems, Inc., Newton, MA, USA) continuously processes raw EEG signals to produce a single number, or BIS.
Gene_expression (produce) of BIS
17) Confidence 0.43 Published 2006 Journal Crit Care Section Body Doc Link PMC1794465 Disease Relevance 0.09 Pain Relevance 0.14
Combined BIS and StcO2 rates are: BIS ?
Gene_expression (rates) of BIS
18) Confidence 0.43 Published 2006 Journal Crit Care Section Body Doc Link PMC1794465 Disease Relevance 0.84 Pain Relevance 0.39
The aim of the current study was to assess any BIS changes during N2O/O2 sedation in pediatric dentistry.


Gene_expression (changes) of BIS associated with sleep disorders
19) Confidence 0.34 Published 2007 Journal European journal of dentistry Section Body Doc Link PMC2609910 Disease Relevance 0.31 Pain Relevance 0.13
Two research showed that no change in BIS or Cerebral State Index value while the participants breathed 70% N2O in O2 although all of them lost consciousness clinically.29,30 In their research on 22 healthy volunteers who were sedated by low N2O, Hall et al21 reported that no correlation was found with OAA/S and BIS.
Neg (no) Gene_expression (found) of BIS associated with unconsciousness
20) Confidence 0.34 Published 2007 Journal European journal of dentistry Section Body Doc Link PMC2609910 Disease Relevance 0.46 Pain Relevance 0.25

General Comments

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