INT162308

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Context Info
Confidence 0.01
First Reported 2007
Last Reported 2009
Negated 0
Speculated 0
Reported most in Abstract
Documents 3
Total Number 3
Disease Relevance 1.71
Pain Relevance 1.40

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

small molecule metabolic process (GNAS) intracellular (GNAS) GTPase activity (GNAS)
transmembrane transport (GNAS) cytoplasm (GNAS) signal transducer activity (GNAS)
Anatomy Link Frequency
thalamus 2
GNAS (Homo sapiens)
Pain Link Frequency Relevance Heat
agonist 84 100.00 Very High Very High Very High
Thalamus 6 99.68 Very High Very High Very High
Hyperalgesia 4 85.40 High High
induced neuropathy 4 75.00 Quite High
Kinase C 2 75.00 Quite High
peripheral neuropathy 2 72.56 Quite High
Pain 2 71.68 Quite High
Neuropathic pain 2 50.48 Quite High
COX2 1 5.00 Very Low Very Low Very Low
b2 receptor 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Urological Neuroanatomy 6 99.16 Very High Very High Very High
Hyperalgesia 8 92.92 High High
Neuropathic Pain 6 75.00 Quite High
Peripheral Neuropathy 2 72.56 Quite High
Nociception 2 67.04 Quite High
Increased Venous Pressure Under Development 3 5.00 Very Low Very Low Very Low
Thrombosis 2 5.00 Very Low Very Low Very Low
Hypertension 2 5.00 Very Low Very Low Very Low
Stress 2 5.00 Very Low Very Low Very Low
Apoptosis 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
While both TP isoforms undergo rapid agonist-induced phosphorylation in response to TXA2 mimetic U46619 [20,25], TP?
Phosphorylation (phosphorylation) of isoforms associated with agonist
1) Confidence 0.01 Published 2007 Journal Biochim Biophys Acta Section Body Doc Link PMC2680961 Disease Relevance 0 Pain Relevance 0.21
Concurrently, oxaliplatin chronic treatment induced a specific upregulation of gamma isoforms of PKC and increased phosphorylation of gamma/epsilon PKC isoforms within thalamus and PAG.
Phosphorylation (phosphorylation) of isoforms in thalamus associated with urological neuroanatomy and thalamus
2) Confidence 0.00 Published 2009 Journal Pain Section Abstract Doc Link 19683395 Disease Relevance 0.85 Pain Relevance 0.57
Concurrently, oxaliplatin chronic treatment induced a specific upregulation of gamma isoforms of PKC and increased phosphorylation of gamma/epsilon PKC isoforms within thalamus and PAG.
Phosphorylation (phosphorylation) of isoforms in thalamus associated with urological neuroanatomy and thalamus
3) Confidence 0.00 Published 2009 Journal Pain Section Abstract Doc Link 19683395 Disease Relevance 0.86 Pain Relevance 0.62

General Comments

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