INT162319

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Context Info
Confidence 0.46
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 1.60
Pain Relevance 1.04

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Il1b) signal transduction (F2rl1) aging (Il1b)
extracellular region (Il1b) plasma membrane (F2rl1) signal transducer activity (F2rl1)
Anatomy Link Frequency
joint 2
F2rl1 (Mus musculus)
Il1b (Mus musculus)
Pain Link Frequency Relevance Heat
antagonist 1 97.12 Very High Very High Very High
Hyperalgesia 5 93.76 High High
allodynia 3 93.24 High High
agonist 1 87.24 High High
cytokine 2 81.56 Quite High
Inflammation 6 81.20 Quite High
Pain 3 76.24 Quite High
Spontaneous pain 1 58.96 Quite High
Disease Link Frequency Relevance Heat
Pressure And Volume Under Development 4 100.00 Very High Very High Very High
Hyperalgesia 5 93.76 High High
Neuropathic Pain 3 93.24 High High
INFLAMMATION 5 81.20 Quite High
Arthralgia 1 76.24 Quite High
Nociception 3 75.00 Quite High
Arthritis 1 75.00 Quite High
Pain 1 58.00 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
PAR-2 activation did not cause significant joint swelling, but increased IL-1beta concentration which was not influenced by the lack of the TRPV1 channel.
Positive_regulation (activation) of PAR-2 in joint Positive_regulation (increased) of IL-1beta associated with pressure and volume under development
1) Confidence 0.46 Published 2010 Journal Eur J Pain Section Abstract Doc Link 19683949 Disease Relevance 1.60 Pain Relevance 1.04

General Comments

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