INT162329

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Context Info
Confidence 0.03
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.58
Pain Relevance 0.47

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

isomerase activity (Ptges2) cytosol (Ptges2) mitochondrion (Ptges2)
Golgi apparatus (Ptges2) nucleus (Ptges2) DNA binding (Ptges2)
Tmc1 (Mus musculus)
Ptges2 (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 7 100.00 Very High Very High Very High
Analgesic 4 96.92 Very High Very High Very High
Hyperalgesia 1 94.40 High High
Arthritis 1 72.92 Quite High
Disease Link Frequency Relevance Heat
INFLAMMATION 4 100.00 Very High Very High Very High
Hyperalgesia 1 94.40 High High
Disease 1 82.64 Quite High
Arthritis 1 72.92 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Our data suggest that inhibition of mPGES-1 protein expression in acute and chronic inflammatory models by BTH, could provide a potential therapeutic target and a pharmacological tool to discern the role of the inducible enzymes COX-2 and mPGES-1 in inflammatory pathologies.
BTH Negative_regulation (inhibition) of Gene_expression (expression) of mPGES-1 associated with inflammation
1) Confidence 0.03 Published 2009 Journal Eur. J. Pharmacol. Section Abstract Doc Link 19686718 Disease Relevance 0.58 Pain Relevance 0.47

General Comments

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