INT16235

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Context Info
Confidence 0.70
First Reported 1980
Last Reported 2010
Negated 2
Speculated 0
Reported most in Abstract
Documents 27
Total Number 27
Disease Relevance 15.71
Pain Relevance 4.06

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (CGB) small molecule metabolic process (CGB) extracellular region (CGB)
cellular nitrogen compound metabolic process (CGB) cell-cell signaling (CGB)
Anatomy Link Frequency
urine 2
Plasma 1
uterine 1
endometrium 1
parathyroid 1
CGB (Homo sapiens)
Pain Link Frequency Relevance Heat
narcan 19 99.98 Very High Very High Very High
Dopamine 4 99.54 Very High Very High Very High
positron emission tomography 1 99.54 Very High Very High Very High
Dismenorea 6 99.16 Very High Very High Very High
opiate 1 98.44 Very High Very High Very High
antagonist 2 97.80 Very High Very High Very High
imagery 8 97.78 Very High Very High Very High
Pain 9 97.04 Very High Very High Very High
Opioid 3 96.48 Very High Very High Very High
headache 2 94.24 High High
Disease Link Frequency Relevance Heat
Endometriosis (extended) 7 100.00 Very High Very High Very High
Testicular Cancer 8 99.80 Very High Very High Very High
Skin Cancer 6 99.58 Very High Very High Very High
Cancer 54 99.32 Very High Very High Very High
Dysmenorrhea 4 99.16 Very High Very High Very High
Ectopic Pregnancy 15 98.66 Very High Very High Very High
Reprotox - General 3 1 98.50 Very High Very High Very High
Lymphatic System Cancer 2 98.44 Very High Very High Very High
Disease 7 98.24 Very High Very High Very High
Reprotox - General 1 45 98.02 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We conclude that our previous recommendations for determining the rate of increase of human chorionic gonadotropin in serum from paired samples do not require revision at this time.
Positive_regulation (increase) of chorionic gonadotropin
1) Confidence 0.70 Published 1987 Journal Am. J. Obstet. Gynecol. Section Abstract Doc Link 3605270 Disease Relevance 0.24 Pain Relevance 0.05
However, serum beta-human chorionic gonadotropin level increased after the operation, and histopathologic results did not show evidence of pregnancy in either right ovary or endometrium.
Positive_regulation (increased) of chorionic gonadotropin in right ovary
2) Confidence 0.61 Published 2008 Journal Journal of minimally invasive gynecology Section Abstract Doc Link 18312999 Disease Relevance 0.77 Pain Relevance 0.26
Although human chorionic gonadotropin level in the serum and urine was transiently elevated, it normalized before surgery.
Positive_regulation (elevated) of chorionic gonadotropin in urine
3) Confidence 0.60 Published 1997 Journal No Shinkei Geka Section Abstract Doc Link 9181593 Disease Relevance 1.54 Pain Relevance 0.08
After he was treated with 2 courses of first-line chemotherapy consisting of peplomycin, etoposide, and cisplatin, which were followed by 2 courses of high-dose chemotherapy with carboplatin, etoposide, and ifosfamide, the metastatic lesions were nearly in complete response on MRI and bone scintigraphy and the result of fluorodeoxyglucose-positron emission tomography was negative, but the hCG-beta level remained slightly elevated.
Positive_regulation (elevated) of hCG-beta associated with positron emission tomography and imagery
4) Confidence 0.57 Published 2005 Journal Hinyokika Kiyo Section Abstract Doc Link 16440733 Disease Relevance 0.65 Pain Relevance 0.25
CONCLUSION: Early diagnosis of intramural pregnancy by skipped menstruation, elevated beta human chorionic gonadotropin (beta-hCG) and intramural cyst not connected the with the endometrium and with no other possible sites of ectopic pregnancy allows the clinician to plan the conservative treatment method at the optimum time, with more opportunity for conservation of fertility.


Positive_regulation (elevated) of chorionic gonadotropin in endometrium
5) Confidence 0.55 Published 2009 Journal J Reprod Med Section Body Doc Link 19438169 Disease Relevance 0.08 Pain Relevance 0
Since the beta-human chorionic gonadotropin (beta-hCG) level was increased to 20.46 mIU/ml on the preoperative blood test, incisional biopsy was performed through a Chamberlain incision to rule out the mediastinal germ cell tumors.
Positive_regulation (increased) of gonadotropin in germ cell associated with germ cell and embryonal neoplasms
6) Confidence 0.55 Published 2010 Journal Interact Cardiovasc Thorac Surg Section Abstract Doc Link 20421278 Disease Relevance 0.35 Pain Relevance 0.09
Diagnostic uterine curettage may be appropriate in patients who are hemodynamically stable and whose beta subunit of human chorionic gonadotropin levels are not increasing as expected.
Neg (not) Positive_regulation (increasing) of chorionic gonadotropin in uterine
7) Confidence 0.54 Published 2005 Journal Am Fam Physician Section Abstract Doc Link 16300032 Disease Relevance 0.90 Pain Relevance 0.11
Seventeen (19%) of 88 patients could not be allotted to the human chorionic gonadotropin categories for which nomograms of the doubling time of human chorionic gonadotropin have been derived.
Neg (not) Positive_regulation (allotted) of chorionic gonadotropin
8) Confidence 0.50 Published 1987 Journal Am. J. Obstet. Gynecol. Section Abstract Doc Link 3605270 Disease Relevance 0.34 Pain Relevance 0.06
Doubling times of human chorionic gonadotropin increase in early viable intrauterine pregnancies.
Positive_regulation (increase) of chorionic gonadotropin
9) Confidence 0.50 Published 1987 Journal Am. J. Obstet. Gynecol. Section Abstract Doc Link 3605270 Disease Relevance 0.42 Pain Relevance 0.09
None of the four males tested had elevated serum gonadotropin levels.
Positive_regulation (elevated) of serum gonadotropin
10) Confidence 0.40 Published 2000 Journal Blood Section Abstract Doc Link 10706855 Disease Relevance 0.72 Pain Relevance 0.26
Retroperitoneal metastatic squamous cell carcinoma of the tonsil (with elevated beta human chorionic gonadotrophin): a misdiagnosis as extra-gonadal germ cell tumour.
Positive_regulation (elevated) of gonadotrophin in tonsil associated with cancer and skin cancer
11) Confidence 0.32 Published 2006 Journal J Laryngol Otol Section Title Doc Link 16716237 Disease Relevance 1.15 Pain Relevance 0.07
CASE: A multiparous patient with a history of cesarean hysterectomy 12 years before presented to the emergency department with abdominal pain and incidental positive urine beta-human chorionic gonadotrophin (hCG).
Positive_regulation (urine) of gonadotrophin in urine
12) Confidence 0.31 Published 2002 Journal Obstet Gynecol Section Body Doc Link 11975964 Disease Relevance 0.09 Pain Relevance 0
Alpha-fetoprotein was within the normal range, but beta-human chorionic gonadotropin and lactate dehydrogenase were slightly elevated.
Positive_regulation (elevated) of chorionic gonadotropin
13) Confidence 0.28 Published 2006 Journal Hinyokika Kiyo Section Abstract Doc Link 16972632 Disease Relevance 1.09 Pain Relevance 0.09
The essential chemical pathological changes were increased plasma calcium, mid-molecule immuno-reactive parathyroid hormone (iPTH), human chorionic gonadotrophin (hCG) levels.
Positive_regulation (increased) of chorionic gonadotrophin in parathyroid
14) Confidence 0.28 Published 1990 Journal Singapore Med J Section Abstract Doc Link 2333552 Disease Relevance 0.45 Pain Relevance 0.09
The patient remained hyperprolactinaemic and received prolonged therapy with metergoline and bromocriptine which suppressed prolactin to normal and she conceived after induction of ovulation with human menopausal gonadotrophin and human chorionic gonadotrophin.
Positive_regulation (induction) of menopausal gonadotrophin associated with endometriosis (extended)
15) Confidence 0.27 Published 1986 Journal Clin. Endocrinol. (Oxf) Section Abstract Doc Link 3791672 Disease Relevance 0.63 Pain Relevance 0.18
Early ectopic pregnancy screening using vaginal ultrasonographic technology together with measurement of beta human chorionic gonadotropin (beta-hCG) and human chorionic somatomammotropin is possible within the first 2 weeks of the missing menses, prior to the appearance of symptoms.
Positive_regulation (measurement) of chorionic gonadotropin associated with ectopic pregnancy
16) Confidence 0.26 Published 1991 Journal Curr. Opin. Obstet. Gynecol. Section Abstract Doc Link 1813010 Disease Relevance 0.23 Pain Relevance 0.04
In vitro human growth hormone increases human chorionic gonadotropin and progesterone secretion by human placenta at term: evidence of a modulatory role by opioids.
Positive_regulation (increases) of chorionic gonadotropin in placenta associated with narcan and opioid
17) Confidence 0.17 Published 1995 Journal Gynecol. Endocrinol. Section Title Doc Link 7502693 Disease Relevance 0 Pain Relevance 0.47
The serum AFP, beta-subunit of human chorionic gonadotropin (hCG-beta), CEA and CA-19-9 were elevated.
Positive_regulation (elevated) of hCG-beta
18) Confidence 0.15 Published 1994 Journal Jpn. J. Clin. Oncol. Section Abstract Doc Link 8126921 Disease Relevance 1.02 Pain Relevance 0.09
Tumor markers including lactate dehydrogenase (LDH), cancer antigen-125 (CA-125), beta-subunit of human chorionic gonadotropin (beta-hCG) and neuron-specific enolase (NSE) were elevated.
Positive_regulation (elevated) of chorionic gonadotropin in neuron associated with cancer
19) Confidence 0.14 Published 2004 Journal J. Pediatr. Surg. Section Abstract Doc Link 15359410 Disease Relevance 0.62 Pain Relevance 0.14
Normal circulating 17beta-oestradiol (E2) levels showed an enhanced response to human chorionic gonadotrophin (hCG) testing, which led to a reduced testosterone (T)/E2 ratio.
Positive_regulation (response) of gonadotrophin
20) Confidence 0.14 Published 2005 Journal Andrologia Section Abstract Doc Link 15644061 Disease Relevance 0.55 Pain Relevance 0.09

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