INT162398

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Context Info
Confidence 0.43
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 2
Disease Relevance 2.11
Pain Relevance 0.93

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
skin 1
LCE3A (Homo sapiens)
Pain Link Frequency Relevance Heat
psoriasis 36 99.22 Very High Very High Very High
Pain 2 96.08 Very High Very High Very High
cytokine 2 72.08 Quite High
Disease Link Frequency Relevance Heat
Psoriasis 38 99.22 Very High Very High Very High
Skin Diseases 4 95.24 Very High Very High Very High
Disease 10 83.80 Quite High
Immune System Diseases 2 61.68 Quite High
Genetic Predisposition To Disease 2 29.24 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Meanwhile, another group also identified a deletion comprising and LCE gene cluster of LCE3B and LCE3C, which is significantly associated with a risk of psoriasis in Spain, Netherland, Italy and USA.
Regulation (cluster) of LCE associated with psoriasis
1) Confidence 0.43 Published 2009 Journal Zhejiang Da Xue Xue Bao Yi Xue Ban Section Abstract Doc Link 19693967 Disease Relevance 1.07 Pain Relevance 0.45
Although some of the highlighted genes are already targeted by effective psoriasis therapies, others could become future targets for treatments,especially for the LCE genes, which will be very useful for unlocking new drug targets and tailored treatments for this painful, disfiguring skin disease.
Regulation (targets) of LCE in skin associated with pain, psoriasis and skin diseases
2) Confidence 0.26 Published 2009 Journal Zhejiang Da Xue Xue Bao Yi Xue Ban Section Abstract Doc Link 19693967 Disease Relevance 1.04 Pain Relevance 0.48

General Comments

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