INT1624

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Context Info
Confidence 0.76
First Reported 1975
Last Reported 2011
Negated 14
Speculated 3
Reported most in Abstract
Documents 212
Total Number 222
Disease Relevance 180.44
Pain Relevance 34.21

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
T-cell 8
CeA 6
epithelium 5
lung 4
neurons 4
Cea (Mus musculus)
Pain Link Frequency Relevance Heat
amygdala 476 100.00 Very High Very High Very High
GABAergic 128 100.00 Very High Very High Very High
Central grey 66 100.00 Very High Very High Very High
Somatostatin 63 100.00 Very High Very High Very High
analgesia 55 100.00 Very High Very High Very High
projection neuron 18 100.00 Very High Very High Very High
epidural 17 100.00 Very High Very High Very High
anesthesia 47 99.92 Very High Very High Very High
Dismenorea 3 99.74 Very High Very High Very High
agonist 9 99.68 Very High Very High Very High
Disease Link Frequency Relevance Heat
Cancer 5298 100.00 Very High Very High Very High
Pancreatic Cancer 598 100.00 Very High Very High Very High
Adenocarcinoma 296 100.00 Very High Very High Very High
Breast Cancer 262 100.00 Very High Very High Very High
Urological Neuroanatomy 66 100.00 Very High Very High Very High
Pox Virus Infection 363 99.98 Very High Very High Very High
Cyst 130 99.98 Very High Very High Very High
Mucinous Adenocarcinoma 39 99.98 Very High Very High Very High
Abscess 12 99.98 Very High Very High Very High
Targeted Disruption 32 99.96 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Carcinoembryonic antigen (CEA) is expressed in a wide variety of adenocarcinomas, and it is well recognized that cancer patients are immunologically "tolerant" to CEA.
Gene_expression (expressed) of CEA associated with adenocarcinoma and cancer
1) Confidence 0.76 Published 1997 Journal Clin. Cancer Res. Section Abstract Doc Link 9815809 Disease Relevance 0.34 Pain Relevance 0.04
When transgenic mice that express the human carcinoembryonic antigen (CEA) gene (CEA transgenic) were bred with mice bearing a mutation in the Apc(Delta850) gene (multiple intestinal neoplasia mice), the progeny (CEA transgenic/multiple intestinal neoplasia) spontaneously develop multiple intestinal neoplasms that overexpress CEA and COX-2.
Gene_expression (express) of CEA associated with targeted disruption and intestinal cancer
2) Confidence 0.76 Published 2004 Journal Cancer Res. Section Abstract Doc Link 15150127 Disease Relevance 1.14 Pain Relevance 0.07
When transgenic mice that express the human carcinoembryonic antigen (CEA) gene (CEA transgenic) were bred with mice bearing a mutation in the Apc(Delta850) gene (multiple intestinal neoplasia mice), the progeny (CEA transgenic/multiple intestinal neoplasia) spontaneously develop multiple intestinal neoplasms that overexpress CEA and COX-2.
Gene_expression (overexpress) of CEA associated with targeted disruption and intestinal cancer
3) Confidence 0.76 Published 2004 Journal Cancer Res. Section Abstract Doc Link 15150127 Disease Relevance 1.31 Pain Relevance 0.05
Both tumor reduction and improved overall survival were achieved without any evidence of autoimmunity directed at CEA-expressing or other normal tissues.
Gene_expression (expressing) of CEA associated with autoimmune disease and cancer
4) Confidence 0.76 Published 2004 Journal Cancer Res. Section Abstract Doc Link 15150127 Disease Relevance 0.97 Pain Relevance 0
The relationship between pre-operative levels of carcino-embryonic antigen (CEA), resectability of the primary tumour, the extent of tumour spread and subsequent survival was studied in 333 patients with colorectal cancer.
Gene_expression (levels) of CEA associated with cancer and colon cancer
5) Confidence 0.75 Published 1984 Journal Br J Surg Section Abstract Doc Link 6199071 Disease Relevance 0.50 Pain Relevance 0.13
This is the first case reported in the literature of a true benign splenic cyst producing high levels of CEA and CA 19-9 in serum and cystic fluid.
Gene_expression (producing) of CEA associated with cyst
6) Confidence 0.71 Published 1998 Journal Am Surg Section Abstract Doc Link 9843333 Disease Relevance 0.62 Pain Relevance 0.07
Circulating CEA levels were determined in 102 patients wtih histologically proven pancreatic carcinoma and 26 patients with chronic pancreatitis.
Gene_expression (levels) of CEA associated with pancreatic cancer and chronic pancreatitis
7) Confidence 0.67 Published 1978 Journal Cancer Section Abstract Doc Link 709516 Disease Relevance 0.64 Pain Relevance 0.10
All tumors were positive for mucicarmine and carcinoembryonic antigen (CEA).
Gene_expression (positive) of CEA associated with cancer
8) Confidence 0.67 Published 1987 Journal Int. J. Gynecol. Pathol. Section Abstract Doc Link 2826354 Disease Relevance 1.20 Pain Relevance 0.08
The tumor markers, carcinoembryonic antigen (CEA) and CA 19-9 were normal in 11 patients and elevated in one patient, whereas only CA 19-9 was elevated in three others.
Gene_expression (elevated) of CEA associated with cancer
9) Confidence 0.67 Published 1991 Journal Cancer Section Abstract Doc Link 2013042 Disease Relevance 0.66 Pain Relevance 0
Histologic examination showed papillary proliferations of well-differentiated, mucus-secreting cells that occasionally stained for carcinoembryonic antigen (CEA) and carbohydrate antigen (CA 19-9).
Gene_expression (stained) of CEA
10) Confidence 0.67 Published 1989 Journal Cancer Section Abstract Doc Link 2548703 Disease Relevance 0.70 Pain Relevance 0.09
[A case of lumbar intradural and epidural abscesses presenting with elevated serum carcinoembryonic antigen (CEA) and carbohydrate antigen 19-9 (CA19-9)].
Gene_expression (presenting) of CEA associated with epidural and abscess
11) Confidence 0.67 Published 2003 Journal No To Shinkei Section Title Doc Link 12833889 Disease Relevance 0.62 Pain Relevance 0.19
We studied serum carcinoembryonic antigen (CEA) levels in 82 patients.
Gene_expression (levels) of CEA
12) Confidence 0.66 Published 1979 Journal Gastroenterol. Jpn. Section Abstract Doc Link 221303 Disease Relevance 0.79 Pain Relevance 0
A preliminary study has also shown that CEA can be extracted from rheumatoid synovial membranes but was not detected in a normal synovium, further indicating that the source of this antigen in RA may be the inflamed synovium.
Neg (not) Gene_expression (detected) of CEA in synovium associated with rheumatoid arthritis
13) Confidence 0.64 Published 1975 Journal Rheumatol Rehabil Section Abstract Doc Link 1121634 Disease Relevance 0.75 Pain Relevance 0.25
CEA expressed in large quantities in approximately 95% of colorectal carcinomas, and the relationship between serum CEA (s-CEA) level and colorectal cancer has been studied extensively.
Gene_expression (expressed) of CEA associated with colon cancer
14) Confidence 0.64 Published 2005 Journal Journal of Korean Medical Science Section Body Doc Link PMC2782159 Disease Relevance 0.87 Pain Relevance 0
Thus, enhanced expression of CEA may confer on cancer cells the ability to invade adjacent tissues and to metastasize to lymph nodes or distant organs.
Gene_expression (expression) of CEA in lymph nodes associated with cancer
15) Confidence 0.64 Published 2005 Journal Journal of Korean Medical Science Section Body Doc Link PMC2782159 Disease Relevance 1.16 Pain Relevance 0
CEA is expressed throughout life in normal adult tissues, including the colon, stomach, tongue, cervix, and prostate (1, 12).
Gene_expression (expressed) of CEA in cervix
16) Confidence 0.64 Published 2005 Journal Journal of Korean Medical Science Section Body Doc Link PMC2782159 Disease Relevance 0.52 Pain Relevance 0
Comparative studies of pancreatic enzymes carbohydrate antigen 19-9 (CA 19-9) and carcinoembryonic antigen (CEA) were performed in various pancreatic disease.
Gene_expression (studies) of CEA associated with pancreatitis
17) Confidence 0.63 Published 1985 Journal Am. J. Gastroenterol. Section Abstract Doc Link 2411125 Disease Relevance 0.84 Pain Relevance 0.18
Pathological levels of the tumor markers carcinoembryonic antigen (CEA) and CA 19-9 are frequently found.
Gene_expression (levels) of CEA associated with cancer
18) Confidence 0.60 Published 1994 Journal Leber Magen Darm Section Abstract Doc Link 7531268 Disease Relevance 1.25 Pain Relevance 0.08
The postoperative sharp drops of serum CEA levels are useful for judging the adequacy of this procedure.
Gene_expression (levels) of CEA
19) Confidence 0.60 Published 1984 Journal Nippon Geka Gakkai Zasshi Section Abstract Doc Link 6749100 Disease Relevance 0.56 Pain Relevance 0.10
The response was assessed to be no change, but the levels of carcinoembryonic antigen (CEA) and carbohydrate antigen (CA) 19-9 improved from 7,028 ng/ml and 726 U/ml 3 weeks after surgery to 2,832 ng/ml and 281 U/ml, respectively.
Gene_expression (levels) of CEA
20) Confidence 0.60 Published 2005 Journal Gan To Kagaku Ryoho Section Abstract Doc Link 16121921 Disease Relevance 0.96 Pain Relevance 0.24

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