INT162441

Context Info Confidence 0.34 First Reported 2009 Last Reported 2009 Negated 0 Speculated 0 Reported most in Abstract Documents 1 Total Number 1 Disease Relevance 0.27 Pain Relevance 0.30

cytosol (Alox5) nuclear envelope (Alox5) oxidoreductase activity (Alox5) nucleus (Alox5) cytoplasm (Alox5)

Alox5 (Mus musculus)

Pain Link Frequency Relevance Heat IPN 1 97.76 Hyperalgesia 1 96.24 Analgesic 1 84.88 Spinal cord 1 51.52 nociceptor 1 25.00

Disease Link Frequency Relevance Heat Inflammatory Pain 1 97.76 Hyperalgesia 1 96.24 Nociception 1 75.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

We found that the number of motifs which describe the colocalization of 5-lipoxygenase (5-LO) or 12-LO with other proteins increased disproportionally after dipyrone treatment.

Positive_regulation (increased) of Localization (colocalization) of 5-LO

1) Confidence 0.34 Published 2009 Journal J. Proteome Res. Section Abstract Doc Link 19697962 Disease Relevance 0.27 Pain Relevance 0.30

General Comments

This test has worked.