INT162478

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Context Info
Confidence 0.75
First Reported 2009
Last Reported 2009
Negated 1
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 1.39
Pain Relevance 0.08

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

KRT6B (Homo sapiens)
Pain Link Frequency Relevance Heat
Bile 1 92.24 High High
Inflammation 1 77.44 Quite High
fibrosis 6 25.48 Quite Low
Pain 2 10.00 Low Low
cva 6 5.00 Very Low Very Low Very Low
imagery 4 5.00 Very Low Very Low Very Low
abdominal pain 2 5.00 Very Low Very Low Very Low
Crohn's disease 2 5.00 Very Low Very Low Very Low
alcohol 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Necrosis 4 91.52 High High
Cancer 25 89.12 High High
Hemangiosarcoma 32 85.92 High High
INFLAMMATION 1 77.44 Quite High
Malignant Neoplastic Disease 12 74.52 Quite High
Serositis 1 68.36 Quite High
Sarcoma 2 60.32 Quite High
Disease 7 56.04 Quite High
Recurrence 3 50.08 Quite High
Pachyonychia Congenita 2 50.00 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
OBJECTIVE: Determine if mTOR inhibitors (rapamycin, temsirolimus or everolimus) are viable drug candidates for treatment of PC and other disorders caused by inappropriate expression of K6a and K6b.
Gene_expression (expression) of K6b
1) Confidence 0.75 Published 2009 Journal J. Dermatol. Sci. Section Body Doc Link 19699613 Disease Relevance 0 Pain Relevance 0
Positive immunohistochemical stains included: CD31, CD34, Podoplanin (D2–40), EMA, and Factor VIII Ag, while Keratin CAM 5.2, Keratin MAK 6, Keratin AE1–AE3, and HepPar1 were negative.
Neg (negative) Gene_expression (negative) of Keratin MAK 6
2) Confidence 0.16 Published 2009 Journal Rare Tumors Section Body Doc Link PMC2994458 Disease Relevance 1.39 Pain Relevance 0.08

General Comments

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