INT162572

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Context Info
Confidence 0.02
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 4
Disease Relevance 0.30
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (Wnt5a) signal transduction (Wnt5a) extracellular space (Wnt5a)
extracellular region (Wnt5a) proteinaceous extracellular matrix (Wnt5a) plasma membrane (Wnt5a)
Anatomy Link Frequency
chondrocytes 4
Wnt5a (Mus musculus)
Pain Link Frequency Relevance Heat
metalloproteinase 8 50.00 Quite Low
Snapping jaw 8 50.00 Quite Low
Disease Link Frequency Relevance Heat
Temporomandibular Joint Syndrome 8 93.92 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Purified Wnt-5A protein and transfection with Wnt-5A expression vector promoted the expression of MMP-1, MMP-3, MMP-9, and MMP-13.
Positive_regulation (transfection) of Gene_expression (transfection) of Wnt-5A
1) Confidence 0.02 Published 2009 Journal Arthritis Rheum. Section Body Doc Link 19714632 Disease Relevance 0.07 Pain Relevance 0
Purified Wnt-5A protein and transfection with Wnt-5A expression vector promoted the expression of MMP-1, MMP-3, MMP-9, and MMP-13.
Positive_regulation (transfection) of Gene_expression (expression) of Wnt-5A
2) Confidence 0.02 Published 2009 Journal Arthritis Rheum. Section Body Doc Link 19714632 Disease Relevance 0.07 Pain Relevance 0
RESULTS: Treatment of rabbit condylar chondrocytes with IL-1beta up-regulated Wnt-5A expression.
Positive_regulation (regulated) of Gene_expression (expression) of Wnt-5A in chondrocytes
3) Confidence 0.02 Published 2009 Journal Arthritis Rheum. Section Body Doc Link 19714632 Disease Relevance 0.07 Pain Relevance 0
METHODS: Primary rabbit condylar chondrocytes were treated with IL-1beta, purified Wnt-5A protein, or both and transfected with Wnt-5A expression vector.
Positive_regulation (transfected) of Gene_expression (expression) of Wnt-5A in chondrocytes
4) Confidence 0.02 Published 2009 Journal Arthritis Rheum. Section Body Doc Link 19714632 Disease Relevance 0.09 Pain Relevance 0

General Comments

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