INT1626

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Context Info
Confidence 0.21
First Reported 1979
Last Reported 2011
Negated 0
Speculated 0
Reported most in Body
Documents 8
Total Number 8
Disease Relevance 7.86
Pain Relevance 0.34

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transport (Cog1) Golgi apparatus (Cog1)
Anatomy Link Frequency
monocytes 1
endothelial cells 1
connective tissue 1
apoptotic cells 1
Cog1 (Mus musculus)
Pain Link Frequency Relevance Heat
chemokine 2 94.96 High High
headache 2 91.52 High High
Angina 3 78.32 Quite High
antagonist 2 68.28 Quite High
tolerance 2 64.60 Quite High
cytokine 6 38.20 Quite Low
Inflammation 14 26.60 Quite Low
aspirin 5 16.04 Low Low
Bile 9 7.12 Low Low
cva 21 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Disorder Of Lipid Metabolism 69 99.92 Very High Very High Very High
Disease 63 97.96 Very High Very High Very High
Hyperlipoproteinemia Type Ii 66 97.88 Very High Very High Very High
Hyperlipidemia 24 97.80 Very High Very High Very High
Apoptosis 9 97.28 Very High Very High Very High
Death 14 95.00 High High
Coma 2 94.60 High High
Convulsion 3 92.80 High High
Psychosis 1 92.40 High High
Headache 2 91.52 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
After 7 days of culture, endothelial cells differentiated from EPCs were identified as adherent cells with 1,1'-dioctadecyl-3,3,3',3'-tetramethyl-indocarbocyanine-labeled acetylated low density lipoprotein (Dil-Ac-LDL) uptake and lectin binding under a fluorescent microscope.
low density lipoprotein Binding (binding) of in endothelial cells
1) Confidence 0.21 Published 2006 Journal Hypertens. Res. Section Abstract Doc Link 17378377 Disease Relevance 0.16 Pain Relevance 0.08
These results were not explained by the possible associations of low density lipoprotein cholesterol or triglycerides with HDL cholesterol.
low density lipoprotein Binding (associations) of associated with disorder of lipid metabolism
2) Confidence 0.09 Published 1979 Journal Am. J. Epidemiol. Section Abstract Doc Link 222134 Disease Relevance 1.93 Pain Relevance 0.06
The class A macrophage scavenger receptor (SR-A) is the prototypic member of a large family of membrane receptors that bind oxidized low density lipoprotein and a wide variety of other ligands many of which are derived from apoptotic cells and pathogens [4].
low density lipoprotein Binding (bind) of in apoptotic cells associated with apoptosis
3) Confidence 0.06 Published 2006 Journal BMC Microbiol Section Body Doc Link PMC1562429 Disease Relevance 1.84 Pain Relevance 0.09
Lipoproteins consist of apolipoproteins, phospholipids, cholesterol, triacyclglyerols, and cholesteryl esters and it is these that define the particle's buoyant density and enables their separation into four major classes: high-density lipoprotein, low-density lipoprotein, very low-density lipoprotein (HDL, LDL, and VLDL, resp.), and chylomicrons.
low-density lipoprotein Binding (separation) of associated with disorder of lipid metabolism
4) Confidence 0.06 Published 2011 Journal Journal of Biomedicine and Biotechnology Section Body Doc Link PMC2975993 Disease Relevance 1.07 Pain Relevance 0
Lipoproteins consist of apolipoproteins, phospholipids, cholesterol, triacyclglyerols, and cholesteryl esters and it is these that define the particle's buoyant density and enables their separation into four major classes: high-density lipoprotein, low-density lipoprotein, very low-density lipoprotein (HDL, LDL, and VLDL, resp.), and chylomicrons.
low-density lipoprotein Binding (separation) of associated with disorder of lipid metabolism
5) Confidence 0.05 Published 2011 Journal Journal of Biomedicine and Biotechnology Section Body Doc Link PMC2975993 Disease Relevance 1.08 Pain Relevance 0
Familial hypercholesterolaemia (FH) is primarily an autosomal dominant disorder, characterised by a lifelong elevation of serum cholesterol bound to low-density lipoprotein (LDL).
low-density lipoprotein Binding (bound) of associated with hyperlipoproteinemia type ii and hyperlipidemia
6) Confidence 0.04 Published 2010 Journal Int Arch Med Section Body Doc Link PMC3016243 Disease Relevance 0.40 Pain Relevance 0
At the cellular and molecular levels, our results are supported by the fact that insulin has demonstrated proliferative effects on cultured vascular smooth muscle cells; it also enhances lipid synthesis and low density lipoprotein binding to these cells as well as connective tissue synthesis in arterial wall (Stout 1992; Bouguerra et al 2001).
low density lipoprotein Binding (binding) of in connective tissue
7) Confidence 0.03 Published 2006 Journal Vascular Health and Risk Management Section Body Doc Link PMC1994018 Disease Relevance 1.40 Pain Relevance 0.07
The first in vitro characterizations of putative EPCs were done by uptake of acetylated low density lipoprotein and Ulex europaeus lectin binding and these capabilities were shown to be shared by monocytes.
low density lipoprotein Binding (binding) of in monocytes
8) Confidence 0.02 Published 2008 Journal Biologics : Targets & Therapy Section Body Doc Link PMC2721378 Disease Relevance 0 Pain Relevance 0.05

General Comments

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