INT162635

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.49
First Reported 2009
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 5
Disease Relevance 4.86
Pain Relevance 0.78

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (PTX3)
Anatomy Link Frequency
coronary artery 6
Blood 2
fat 2
PTX3 (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 38 100.00 Very High Very High Very High
cytokine 8 100.00 Very High Very High Very High
Angina 7 95.64 Very High Very High Very High
Inflammatory stimuli 1 84.04 Quite High
Inflammatory marker 21 75.00 Quite High
ischemia 8 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 59 100.00 Very High Very High Very High
Coronary Artery Disease 12 99.48 Very High Very High Very High
Natriuresis 1 98.56 Very High Very High Very High
Myocardial Infarction 108 97.96 Very High Very High Very High
Acute Coronary Syndrome 3 96.36 Very High Very High Very High
Angina 3 95.64 Very High Very High Very High
Metabolic Syndrome 108 93.76 High High
Obesity 52 86.40 High High
Death 2 83.44 Quite High
Atherosclerosis 1 82.28 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
, and it has been known to be specifically and abundantly present in cardiac muscle.7-9) It has been shown that, unlike CRP, serum PTX3 is rapidly induced by several inflammatory cytokines and primarily secreted from vascular endothelial cells.17) PTX3 secreted from cardiac vascular endothelial cells in response to several immunological signals18) is elevated not only in coronary artery diseases, but also in heart failure and has been reported to correlate with prognosis in heart failure.11)
Positive_regulation (response) of Localization (secreted) of PTX3 in coronary artery associated with coronary artery disease, inflammation, myocardial infarction and cytokine
1) Confidence 0.49 Published 2010 Journal Korean Circulation Journal Section Body Doc Link PMC2910286 Disease Relevance 0.92 Pain Relevance 0.14
In our study, in acute myocardial infarction patients, subcutaneous fat and visceral fat were measured quantitatively by FAT-CT, and it was observed that increases in PTX3 concentration were significantly associated with increases in visceral fat and abdominal fat areas.
Positive_regulation (increases) of Localization (concentration) of PTX3 in fat associated with myocardial infarction
2) Confidence 0.49 Published 2010 Journal Korean Circulation Journal Section Body Doc Link PMC2910286 Disease Relevance 1.05 Pain Relevance 0.11
, and it has been known to be specifically and abundantly present in cardiac muscle.7-9) It has been shown that, unlike CRP, serum PTX3 is rapidly induced by several inflammatory cytokines and primarily secreted from vascular endothelial cells.17) PTX3 secreted from cardiac vascular endothelial cells in response to several immunological signals18) is elevated not only in coronary artery diseases, but also in heart failure and has been reported to correlate with prognosis in heart failure.11)
Positive_regulation (elevated) of Localization (secreted) of PTX3 in coronary artery associated with coronary artery disease, inflammation, myocardial infarction and cytokine
3) Confidence 0.49 Published 2010 Journal Korean Circulation Journal Section Body Doc Link PMC2910286 Disease Relevance 1.02 Pain Relevance 0.14
, and it has been known to be specifically and abundantly present in cardiac muscle.7-9) It has been shown that, unlike CRP, serum PTX3 is rapidly induced by several inflammatory cytokines and primarily secreted from vascular endothelial cells.17) PTX3 secreted from cardiac vascular endothelial cells in response to several immunological signals18) is elevated not only in coronary artery diseases, but also in heart failure and has been reported to correlate with prognosis in heart failure.11)
Positive_regulation (elevated) of Localization (secreted) of PTX3 in coronary artery associated with coronary artery disease, inflammation, myocardial infarction and cytokine
4) Confidence 0.49 Published 2010 Journal Korean Circulation Journal Section Body Doc Link PMC2910286 Disease Relevance 0.95 Pain Relevance 0.14
Blood samples were taken on admission for measurement of PTX3, high sensitive C-reactive protein (hsCRP), B-type natriuretic peptide (BNP), and troponin T.
Positive_regulation (sensitive) of Localization (measurement) of PTX3 in Blood associated with natriuresis
5) Confidence 0.47 Published 2009 Journal Thromb. Haemost. Section Abstract Doc Link 19718477 Disease Relevance 0.92 Pain Relevance 0.25

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox