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Context Info
Confidence 0.45
First Reported 2003
Last Reported 2009
Negated 0
Speculated 1
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 1.39
Pain Relevance 0.65

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (KIR3DL1)
KIR3DL1 (Homo sapiens)
Pain Link Frequency Relevance Heat
spinal inflammation 97 98.56 Very High Very High Very High
rheumatoid arthritis 7 73.28 Quite High
Arthritis 4 43.92 Quite Low
Inflammation 6 41.68 Quite Low
spondylitis 4 5.00 Very Low Very Low Very Low
cytokine 3 5.00 Very Low Very Low Very Low
Multiple sclerosis 2 5.00 Very Low Very Low Very Low
tolerance 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Low Back Pain 97 98.56 Very High Very High Very High
Spondylarthropathies 1 97.52 Very High Very High Very High
Spondylarthritis 1 83.52 Quite High
Ankylosing Spondylitis 4 73.60 Quite High
Rheumatoid Arthritis 8 73.28 Quite High
Disease 31 69.04 Quite High
Cytomegalovirus Infection 13 63.96 Quite High
Epstein-barr Virus 13 62.16 Quite High
Skin Cancer 1 57.92 Quite High
Sacroiliitis 1 49.76 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Here, we have analysed the possible influence of KIR genotypes in the susceptibility to AS in B27 individuals.
Spec (possible) Regulation (influence) of KIR associated with spinal inflammation
1) Confidence 0.45 Published 2006 Journal Arthritis Res Ther Section Body Doc Link PMC1779409 Disease Relevance 0.10 Pain Relevance 0.10
Up to the present few studies have experimentally been developed concerning the role of KIR genes in spondyloarthropathies (SpA) and its clear relationship with HLA-B27.
Regulation (role) of KIR
2) Confidence 0.44 Published 2009 Journal Adv. Exp. Med. Biol. Section Abstract Doc Link 19731638 Disease Relevance 0.23 Pain Relevance 0.15
These aberrant forms of HLA-B27 can be recognized by immunomodulatory killer cell immunoglobulin receptors, such as KIR3DL1 and KIR3DL2, and the immunoglobulin-like transcript ILT-4.
Regulation (immunomodulatory) of KIR3DL1
3) Confidence 0.27 Published 2003 Journal Arthritis Res Ther Section Body Doc Link PMC193730 Disease Relevance 1.06 Pain Relevance 0.41

General Comments

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