INT162790

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Context Info
Confidence 0.36
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.51
Pain Relevance 0.57

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (TLR4, NOD2) cytoplasm (TLR4, NOD2) cytosol (NOD2)
signal transduction (TLR4) intracellular (TLR4) enzyme binding (NOD2)
Anatomy Link Frequency
HDPF 1
TLR4 (Homo sapiens)
NOD2 (Homo sapiens)
Pain Link Frequency Relevance Heat
agonist 3 100.00 Very High Very High Very High
Inflammatory mediators 3 98.20 Very High Very High Very High
chemokine 1 92.80 High High
cytokine 1 92.32 High High
pulpitis 2 77.76 Quite High
Inflammation 1 75.72 Quite High
COX2 1 25.00 Low Low
Disease Link Frequency Relevance Heat
INFLAMMATION 4 98.20 Very High Very High Very High
Adhesions 1 93.20 High High
Pulpitis 2 77.20 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
More over, the NOD2 agonist acted synergistically with the TLR2, not the TLR4, agonist to stimulate the production of pro-inflammatory mediators in HDPF.
TLR4 Binding (acted) of NOD2 in HDPF associated with inflammatory mediators and agonist
1) Confidence 0.36 Published 2009 Journal J. Dent. Res. Section Abstract Doc Link 19734466 Disease Relevance 0.51 Pain Relevance 0.57

General Comments

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