INT162791

Context Info Confidence 0.13 First Reported 2009 Last Reported 2010 Negated 0 Speculated 0 Reported most in Body Documents 2 Total Number 3 Disease Relevance 0.58 Pain Relevance 0.55

cytosol (NOD1) signal transduction (NOD1) plasma membrane (NOD1) intracellular (NOD1) cytoplasm (NOD1)

Anatomy Link Frequency eye 1 fibroblasts 1 neural 1 NOD1 (Homo sapiens)

Pain Link Frequency Relevance Heat COX2 1 100.00 Inflammatory mediators 3 97.64 Inflammation 1 95.36 pulpitis 2 93.72 cytokine 1 78.64 chemokine 1 78.20 agonist 3 71.60 addiction 2 12.84 anesthesia 4 5.00 Buprenorphine 2 5.00

Disease Link Frequency Relevance Heat INFLAMMATION 4 97.64 Pulpitis 2 93.72 Adhesions 1 77.72 Ocular Toxicity (including Many Sub-types) 2 68.28 Disease 2 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

The main effect of the Nod/Uv lesions on the interaural tVOR was to reduce sustained eye velocity during steady-state translation.

Regulation (effect) of Nod/Uv in eye

1) Confidence 0.13 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2981566 Disease Relevance 0.07 Pain Relevance 0

Roles of TLR2, TLR4, NOD2, and NOD1 in pulp fibroblasts.

Regulation (Roles) of NOD1 in fibroblasts associated with cox2

2) Confidence 0.11 Published 2009 Journal J. Dent. Res. Section Title Doc Link 19734466 Disease Relevance 0.51 Pain Relevance 0.55

Thus, it appears that there are two separate functional integrators: 1) a tVOR integrator, under control of the Nod/Uv, and 2) the common neural integrator, under control of the floccular complex.

Regulation (control) of Nod/Uv in neural

3) Confidence 0.08 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2981566 Disease Relevance 0 Pain Relevance 0

General Comments

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