INT162803

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Context Info
Confidence 0.44
First Reported 2003
Last Reported 2010
Negated 0
Speculated 1
Reported most in Body
Documents 3
Total Number 4
Disease Relevance 3.68
Pain Relevance 0.81

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (F5) extracellular region (F5) cell adhesion (F5)
plasma membrane (F5)
F5 (Homo sapiens)
Pain Link Frequency Relevance Heat
rheumatoid arthritis 2 99.54 Very High Very High Very High
cva 109 98.44 Very High Very High Very High
abdominal pain 1 75.40 Quite High
Angina 6 73.64 Quite High
spastic colon 1 38.24 Quite Low
aspirin 26 5.00 Very Low Very Low Very Low
epidural 3 5.00 Very Low Very Low Very Low
anesthesia 2 5.00 Very Low Very Low Very Low
Central nervous system 1 5.00 Very Low Very Low Very Low
Inflammation 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Rheumatoid Arthritis 2 99.54 Very High Very High Very High
Thrombophilia 155 99.52 Very High Very High Very High
Thrombosis Related Under Development 58 98.44 Very High Very High Very High
Pulmonary Embolism 45 96.84 Very High Very High Very High
Pre-eclampsia 114 95.00 High High
Thrombosis 79 93.68 High High
Rotator Cuff Tears 16 91.24 High High
Cv General 3 Under Development 9 89.68 High High
Togavirus Infection 123 87.40 High High
Cv General 4 Under Development 2 81.04 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
One patient was being treated for rheumatoid arthritis and the second tested positive for heterozygote factor V Leiden gene mutation, which is a known hypercoagulable condition.
Regulation (positive) of factor V Leiden gene associated with rheumatoid arthritis
1) Confidence 0.44 Published 2008 Journal International Journal of Shoulder Surgery Section Body Doc Link PMC2840827 Disease Relevance 1.99 Pain Relevance 0.65
Thrombophilia workup revealed double heterozygosity for factor V Leiden and prothrombin G20210A mutation.
Regulation (heterozygosity) of factor V associated with thrombophilia
2) Confidence 0.36 Published 2009 Journal Blood Coagul. Fibrinolysis Section Abstract Doc Link 19734780 Disease Relevance 0.76 Pain Relevance 0.12
However, only vF5-3 was neutralized, and vF5-5 was as resistant to neutralization by Hy4 as it was to F5.
Regulation (resistant) of vF5-5
3) Confidence 0.03 Published 2010 Journal PLoS Neglected Tropical Diseases Section Body Doc Link PMC2903468 Disease Relevance 0.14 Pain Relevance 0
Lindqvist et al. [71], in a retrospective study investigated the role of APCR and FV Leiden mutation in 2,480 women enrolled in early pregnancy.
Spec (investigated) Regulation (role) of FV Leiden
4) Confidence 0.01 Published 2003 Journal Reprod Biol Endocrinol Section Body Doc Link PMC305329 Disease Relevance 0.78 Pain Relevance 0.04

General Comments

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